信号通路在胃癌转移中作用的研究进展

doi:10.16352/j.issn.1001-6325.2023.11.1707

摘要/Abstract

摘要： 细胞中不同的信号通路交互作用、互相调控形成一个动态的信号转导网络,参与肿瘤的发生发展,而胃癌的转移就是由各种信号通路调节影响的结果。肿瘤转移通常在临床上与较差的患者预后直接相关,因此深入研究影响胃癌转移的信号通路对晚期胃癌患者的治疗可提供帮助。

关键词: 胃癌, 转移, 转化生长因子β(TGFβ), 磷脂酰肌醇3激酶(PI3K), 信号通路

Abstract: The interaction and mutual regulation of different signaling pathways in cells form a dynamic signal transduction network, which is involved in the development of tumors, as the distant metastasis of gastric cancer is the result of regulation and influence of various signaling pathways. Cancer metastasis is often directly associated with poor prognosis, thus in-depth study of the signaling pathway affecting gastric cancer metastasis is essential strategy to optimize the treatment of advanced gastric cancer patients.

Key words: gastric cancer, metastasis, transforming growth factor-β(TGFβ), phosphatidylinositol 3-kinase(PI3K), signaling pathway

中图分类号:

R735.2

杨蛟洋, 舒格格, 李东宝, 周进. 信号通路在胃癌转移中作用的研究进展[J]. 基础医学与临床, 2023, 43(11): 1707-1712.

YANG Jiaoyang, SHU Gege, LI Dongbao, ZHOU Jin. Research progress of signaling pathways in gastric cancer metastasis[J]. Basic & Clinical Medicine, 2023, 43(11): 1707-1712.

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http://journal11.magtechjournal.com/Jwk_jcyxylc/CN/Y2023/V43/I11/1707

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