中国现代神经疾病杂志 ›› 2025, Vol. 25 ›› Issue (1): 65-71. doi: 10.3969/j.issn.1672-6731.2025.01.009

• 神经调控技术应用与进展 • 上一篇    下一篇

2 中枢性疼痛神经调控治疗进展

甘宇1, 万峻阁2, 李忠华3, 李帅4, 韩帅2,*()   

  1. 1. 110003 辽宁省沈阳市第七人民医院内分泌科
    2. 110004 沈阳, 中国医科大学附属盛京医院神经外科
    3. 223300 江苏省淮安市第五人民医院神经外科
    4. 123000 辽宁省健康产业集团阜新矿总医院神经外科
  • 收稿日期:2024-12-02 出版日期:2025-01-25 发布日期:2025-02-10
  • 通讯作者: 韩帅
  • 作者简介:

    甘宇与万峻阁对本文有同等贡献

    GAN Yu and WAN Jun-ge contributed equally to the article

Progress on neuromodulation for treatment of central pain

Yu GAN1, Jun-ge WAN2, Zhong-hua LI3, Shuai LI4, Shuai HAN2,*()   

  1. 1. Department of Endocrinology, Shenyang Seventh People's Hospital, Shenyang 110003, Liaoning, China
    2. Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning, China
    3. Department of Neurosurgery, the Fifth People's Hospital of Huai'an, Huai'an 223300, Jiangsu, China
    4. Department of Neurosurgery, General Hospital of Fuxin Mining Industry Group, Liaoning Health Industry Group, Fuxin 123000, Liaoning, China
  • Received:2024-12-02 Online:2025-01-25 Published:2025-02-10
  • Contact: Shuai HAN

摘要:

中枢性疼痛由中枢躯体感觉神经系统病变引起,程度剧烈,严重影响生活质量。传统药物治疗作用有限,近年神经调控技术广泛应用于中枢性疼痛的治疗,主要包括脊髓电刺激术和运动皮质电刺激术。本文从二者的原理、临床应用及不良反应方面展开综述,并分析未来研究方向,旨在指导神经调控技术在中枢性疼痛中的应用。

关键词: 疼痛, 电刺激疗法, 综述

Abstract:

Central pain often arises as a sequela of lesions in the central somatosensory nervous system, and the intensity of pain is generally severe, significantly impacting patients' quality of life. Conventional pharmacological therapies usually have limited efficacy. In recent years, neuromodulation technique mainly including spinal cord stimulation (SCS) and motor cortex stimulation (MCS), which have been widely applied in the treatment of central pain. This review provides an overview of the two techniques in terms of their principles, clinical applications and adverse effects, and analyze the future research directions, aiming to guide the application of neuromodulation technique in central pain.

Key words: Pain, Electric stimulation therapy, Review