基础医学与临床 ›› 2015, Vol. 35 ›› Issue (1): 104-107.

• 短篇综述 • 上一篇    下一篇

Annexin A5对于部分相关疾病的作用机制研究进展

高丕尧1,高枫2,甘嘉亮1   

  1. 1. 广西医科大学第一附属医院
    2. 广西医科大学第一附属医院结直肠肛门外科
  • 收稿日期:2014-04-11 修回日期:2014-05-23 出版日期:2015-01-05 发布日期:2014-12-30
  • 通讯作者: 甘嘉亮 E-mail:gjl259@126.com
  • 基金资助:
    国家自然科学基金;广西高校科学技术研究重点项目;广西自然科学基金

Progress in the mechanism of annexin A5 in the related diseases

  • Received:2014-04-11 Revised:2014-05-23 Online:2015-01-05 Published:2014-12-30
  • Supported by:
    the Chinese National Natural Science Foundation

摘要: Annexin A5(膜联蛋白A5)是Ca2+依赖的磷脂结合蛋白家族的一名成员,它存在于组织细胞中,因为其具有的独特结构而参加多种细胞内、外的抗凝、促凋亡等重要功能。并且Annexin A5与系统性红斑狼疮、肿瘤等多种疾病的发病机制有着一定关联性。

关键词: Annexin a5, 疾病, 机制

Abstract: Annexin A5 is a member of Ca2+-dependent Phospholipid Binding Proteins Family. It exists in histocytes. And because of its unique structure, Annexin A5 plays an important role in many critical functions such as cell inside/outside anticoagulation and pro-apoptosis. Moreover, Annexin A5 has certain relevance with many diseases such as systemic lupus erythematosus ,tumour and other diseases.

Key words: Annexin a5, Disease, Mechanism