Progress on the role of mitophagy in myocardial ischemia-reperfusion injury

doi:10.16352/j.issn.1001-6325.2023.11.1723

Abstract

Abstract: Myocardial ischemia-reperfusion injury (MI/RI) is potentially associated with activation of mitophagy through a variety of molecular mechanisms. Moderate mitophagy is effective in maintaining mitochondrial membrane potential and cell membrane structure and function, thereby reducing MI/RI, whereas mitochondrial dysfunction, inadequate clearance or over-activated mitophagy can make MI/RI more severe.

Key words: mitophagy, myocardial ischemia-reperfusion injury (MI/RI), molecular mechanisms, signaling pathway

CLC Number:

MA Congcong, LIU Yang, LYU Yang, WANG Haiping. Progress on the role of mitophagy in myocardial ischemia-reperfusion injury[J]. Basic & Clinical Medicine, 2023, 43(11): 1723-1727.

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URL: http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/10.16352/j.issn.1001-6325.2023.11.1723

http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2023/V43/I11/1723

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