Abstract:

Cerebral ischemia secondary to intracerebral hemorrhage (ICH) in the acute phase can aggravate mortality and disability in ICH patients. The underlying pathophysiology of secondary ischemic is still unclear, and may be closely related to blood pressure fluctuations, hematoma compression, and cerebral small vessel lesions. The prevention methods for this problem include the designation of antihypertensive targets according to cerebral autoregulation (CA) and release of hematoma compression, etc., and the key is to explore the personalized treatment plan for ICH, which can effectively prevent or alleviate the possibility of nerve damage, and aviod secondary cerebral ischemic. This article mainly expounds the pathophysiological mechanism, early diagnosis and prevention of secondary cerebral ischemia after ICH, aiming to provide clinical guidance for individualized secondary prevention of acute ICH.

Key words: Cerebral hemorrhage, Brain ischemia, Review

摘要：

脑出血急性期继发性脑缺血可增加脑出血患者病死率和病残率，但其潜在病理生理学机制仍不清楚，可能与血压波动、血肿压迫及脑小血管病变等密切相关。针对脑出血急性期继发性脑缺血的预防方法主要为，根据脑血流自动调节能力确定降压目标、解除血肿压迫等，其关键在于探索个性化治疗方案，有效预防或减轻神经功能缺损，预防继发性脑缺血。本文主要从脑出血急性期继发性脑缺血的病理生理学机制、早期诊断和预防进行阐述，旨在为临床脑出血急性期个性化二级预防提供指导。

关键词: 脑出血, 脑缺血, 综述