Abstract:

Skull base osseous lesions, including various benign and malignant tumors, and developmental abnormalities like chordomas, osteomas, chondromas, osteosarcomas, fibrous dysplasia (FD), endolymphatic sac tumors, et al, are challenging to treat due to their deep anatomical location near critical nerves and vessels. Surgical treatment demands a balance between complete lesion resection and neural function preservation. In recent years, advances in endoscopy, imaging, intraoperative navigation, proton radiation therapy, and multi-disciplinary team (MDT) have led to continuous optimization of treatment strategies for skull base osseous lesions. This paper briefly reviews the current surgical strategies and breakthroughs for skull base osseous lesions.

Key words: Skull base, Neurosurgical procedures, Neuroendoscopes, Review

摘要：

颅底骨性病变涵盖良性和恶性肿瘤、炎症以及先天性发育异常等多种病变，因其解剖位置深、毗邻重要神经血管，手术治疗极具挑战。随着内镜颅底技术、影像学、术中导航、质子放射治疗及多学科诊疗模式的发展，颅底骨性病变的治疗策略不断优化，本文简述颅底骨性病变的手术治疗现状与突破性进展。

关键词: 颅底, 神经外科手术, 神经内窥镜, 综述