Temporal plus epilepsy定义及其临床特征探究

doi:10.3969/j.issn.1672-6731.2021.07.012

摘要/Abstract

摘要：

内侧颞叶癫是脑网络疾病，多为药物治疗无效者。外科手术后有20%~30%患者仍有发作，其重要原因之一是癫源区超出颞叶内侧，涉及颞叶外侧和颞叶周围区，因此2005年Ryvlin和Kahane提出"TPE"的概念。此后神经电生理尤其是颅内记录、MRI、fMRI和DTI等均证明该类型癫的存在。TPE在临床上具有颞叶内侧及其所涉及区的两种症状。与内侧颞叶癫不同，头皮脑电图异常范围广泛，但不能确定为TPE，颅内电极尤其是立体脑电图是确定TPE必不可少的方法。TPE多为药物难治者，外科手术可全切除癫源区。TPE直译为"颞叶附加癫"，易产生歧义，笔者建议在癫发作分类中增加"多脑叶癫"，包括TPE及其他涉及1个以上脑叶的发作。

关键词: Temporal plus epilepsy (非MeSH词), 多脑叶癫(非MeSH词), 癫,颞叶, 脑电描记术, 综述

Abstract:

Mesial temporal lobe epilepsy (mTLE) is thought to be a network disease, most of them are medical intractable epilepsy. Surgery has benefit outcome, unfortunately, 20%-30% patients with mTLE who undergo surgery fail to achive seizure freedom. One of the causes for failure of surgery is the epileptogenic zone extends from the medial temporal lobe to the lateral and surrending cortices of the temporal lobe. For this reason, Ryvlin and Kahane introduced the conception of temporal plus epilepsy (TPE). Thereafter, the studies of neuroelectrophysiology especially intracranial recordings, MRI, fMRI and DTI have been demenstrated that TPE is a subtype of mTLE. Clinically, the symptoms of TPE should be including both the medial temporal lobe and surrending areas. Scalp EEG recordings are different from the mTLE, since the abnormal findings frenquently exhibit more extensive areas. Therefore, the TPE remain to be determined. Intracranial EEG, epicially SEEG method is especially well-adapted to investigate TPE. TPE is medicinal intractable epilepsy, neurosurgery must be resect the epileptogenic zone totally. If the term temporal plus epilepsy translate to Chinese by word-for-word, what does it means by that? In fact the TPE is a multilobar epilepsy.

Key words: Temporal plus epilepsy (not in MeSH), Multilobe epilepsy (not in MeSH), Epilepsy, temporal lobe, Electroencephalography, Review

王薇薇, 吴逊. Temporal plus epilepsy定义及其临床特征探究[J]. 中国现代神经疾病杂志, 2021, 21(7): 598-605.

WANG Wei-wei, WU Xun. Temporal plus epilepsy: the conception should be attack great importance and inquiring[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2021, 21(7): 598-605.

https://journal11.magtechjournal.com/cjcnn/CN/Y2021/V21/I7/598

参考文献

[1] Barba C, Barbati G, Minotti L, Hoffmann D, Kahane P. Ictal clinical and scalp-EEG findings differentiating temporal lobe epilepsies from temporal ‘plus’ epilepsies[J]. Brain, 2007, 130(Pt 7):1957-1967.
[2] Ryvlin P, Kahane P. The hidden causes of surgery-resistant temporal lobe epilepsy:extratemporal or temporal plus[J]? Curr Opin Neurol, 2005, 18:125-127.
[3] Massot-Tarrús A, Steven DA, McLachlan RS, Mirsattari SM, Diosy D, Parrent AG, Blume WT, Girvin JP, Burneo JG. Outcome of temporal lobe epilepsy surgery evaluated with bitemporal intracranial electrodes recordings[J]. Epilepsy Res, 2016, 127:324-330.
[4] Guedj E, Bonini F, Gavaret M, Trébuchon A, Aubert S, Boucekine M, Boyer L, Carron R, McGonigal A, Bartolomei F. ¹⁸FDG-PET in different subtype of temporal lobe epilepsy:SEEG validation and predictive value[J]. Epilepsia, 2015, 56:414-421.
[5] Bonilha L, Martz GU, Glazier SS, Edwards JC. Subtype of medial lobe epilepsy:influence on temporal lobectomy outcome[J]? Epilepsia, 2012, 53:1-6.
[6] Bartolomei F, Cosandier-Rimele D, McGonigal A, Aubert S, Régis J, Gavaret M, Wendling F, Chauvel P. From mesial temporal lobe to temporoperisylvian seizures:a quantified study of temoral lobe seizure networks[J]. Epilepsia, 2010, 51:2147-2158.
[7] Barba C, Rheims S, Minott L, Guénot M, Hoffmann D, Chabardès S, Isnard J, Kahane P, Ryvlin P. Temporal plus epilepsy is a major determinant of temporal lobe surgery failure[J]. Brain, 2016, 139(Pt 2):444-451.
[8] Salanova V, Markand O, Worth R. Temporal lobe epilepsy:analysis of failures and the role of reoperation[J]. Acta Neurol Scand, 2005, 111:126-133.
[9] Aghakhani Y, Liu X, Jette N, Wiebe S. Epilepsy surgery in patients with bilateral temporal lobe seizures:a systematic review[J]. Epilepsia, 2014, 55:1892-1901.
[10] Blauwblomme T, David O, Minotti L, Job AS, Chassagnon S, Hoffman D, Chabardes S, Kahane P. Prognostic value of insular lobe involvement in temporal lobe epilepsy:a stereoelectroencephalographic study[J]. Epilepsia, 2013, 54:1658-1667.
[11] Andrade-Machado R, Benjumea-Cuartas V. Temporal plus epilepsy:anatomo-electroclinical subtypes[J]. Iran J Neurol, 2016, 15:153-163.
[12] Jobst BC. Temporal plus epilepsy:epileptic territory beyond the temporal lobes[J]. Epilepsy Curr, 2016, 16:305-307.
[13] Barba C, Minotti L, Job AS, Kahane P. The insula in temporal plus epilepsy[J]. J Clin Neurophysiol, 2017, 34:324-327.
[14] Chkhenkeli SA, Šramka M, Rakviashvili TN, Lortkipanidze GS, Magalashvili GE, Bregvadze ESh, Otarashvili A, Gagoshidze TSh. Bitemporal intractable epilepsy:could it be surgically treatable[J]? Stereotact Funct Neurosury, 2013, 91:104-112.
[15] Giulioni M, Martinoni M, Marucci G. Temporal plus epilepsy is a major determinant of temporal lobe surgery failures[J]. Brain, 2016, 139(Pt 7):e35.
[16] Hennessy MJ, Elwes RD, Binnie CD, Polkey CE. Failed surgery for epilepsy:a study of persistence and recurrence of seizures following temporal resection[J]. Brain, 2000, 123 Pt 12:2445-2466.
[17] Kahane P, Barba C, Rheims S, Job-Chapron AS, Minotti L, Ryvlin P. The concept of temporal ‘plus’ epilepsy[J]. Rev Neurol (Paris), 2015, 171:267-272.
[18] Kahane P, Isnard J, Hoffmann D, Guénot M, Barba C, Ostrowsky K, Ryvlin P, Benabid AL, Mauguière F, Munari C. Tempole plus epilepsies:1. Prevalence in epilepsy surgery patients[J]. Epilepsia, 2001, 42(Suppl 7):192.
[19] Bartolomei F, Wendling F, Vignal JP, Kochen S, Bellanger JJ, Badier JM, Le Bouquin-Jeannes R, Chauvel P. Seizures of temporal lobe epilepsy:identification of subtypes by coherence analysis using stereo-electro-encephalography[J]. Clin Neurophysiol, 1999, 110:1741-1754.
[20] Ryvlin P, Kahane P, Isnard J, Chabardes S, Sindou M, Minotti L, Mauguiere F, Benabid AL, Munari C. Temporal plus epilepsiesⅡ:Surgical results[J]. Epilepsia, 2001, 42(Suppl 7):198.
[21] Sarkis RA, Jehi L, Najm IM, Kotagal P, Bingaman WE. Seizure outcomes following multilobar epilepsy surgery[J]. Epilepsia, 2012, 53:44-50.
[22] Haneef Z, Lenartowicz A, Yeh HJ, Levin HS, Engel J Jr, Stern JM. Functional connectivity of hippocampal networks in temporal lobe epilepsy[J]. Epilepsia, 2014, 55:137-145.
[23] Enatsu R, Gonzalez-Martinez J, Bulacio J, Kubota Y, Mosher J, Burgess RC, Najm I, Nair DR. Connections of the limbic network:a corticocortical evoked potential study[J]. Cortex, 2015, 62:20-33.
[24] Lacruz ME, García Seoane JJ, Valentin A, Selway R, Alarcón G. Frontal and temporal functional connections of the living human brain[J]. Eur J Neurosci, 2007, 26:1357-1370.
[25] Isnard J, Guénot M, Sindou M, Mauguière F. Clinical manifestations of insular lobe seizure:a stereo-electroencephalographic study[J]. Epilepsia, 2004, 45:1079-1090.
[26] Ostrowsky K, Isnard J, Ryvlin P, Guénot M, Fischer C, Mauguière F. Functional mapping of the insular cortex:clinical implication in temporal lobe epilepsy[J]. Epilepsia, 2000, 41:681-686.
[27] Mandonnet E, Gatignol P, Duffau H. Evidence for an occipito-temporal tract underlying visual recognition in picture naming[J]. Clin Neurol Neurosurg, 2009, 111:601-605.
[28] Bouilleret V, Dupont S, Spelle L, Baulac M, Samson Y, Semah F. Insular cortex involvement in mesiotemporal lobe epilepsy:a positron emission tomography study[J]. Ann Neurol, 2002, 51:202-208.
[29] Isnard J, Guénot M, Ostrowsky K, Sindou M, Mauguière F. The role of the insular cortex in temporal lobe epilepsy[J]. Ann Neurol, 2000, 48:614-623.
[30] Levitt MR, Ojemann JG, Kuratani J. Insular epilepsy masquerading as multifocal cortical epilepsy as proven by depth electrode[J]. J Neurosurg Pediatr, 2010, 5:365-367.
[31] Hirsch LJ, Spencer SS, Williamson PD, Spencer DD, Mattson RH. Comparison of bitemporal and unitemporal epilepsy defined by depth electroencephalography[J]. Ann Neurol, 1991, 30:340-346.
[32] De Benedictis A, Duffau H, Paradiso B, Grandi E, Balbi S, Granieri E, Colarusso E, Chioffi F, Marras CE, Sarubbo S. Anatomo-functional study of the temporo-parieto-occipital region:dissection, tractographic and brain mapping evidence from a neurosurgical perspective[J]. J Anat, 2014, 225:132-151.
[33] Appel S, Sharan AD, Tracy JI, Evans J, Sperling MR. A comparison of occipital and temporal lobe epilepsies[J]. Acta Neurol Scand, 2015, 132:284-290.
[34] Usui N, Mihara T, Baba K, Matsuda K, Tottori T, Umeoka S, Nakamura F, Terada K, Usui K, Inoue Y. Early seizure propagation from the occipital lobe to medial temporal structures and its surgical implication[J]. Epileptic Disord, 2008, 10:260-265.
[35] Palmini A, Andermann F, Dubeau F, Gloor P, Olivier A, Quesney LF, Salanova V. Occipitotemporal epilepsies:evaluatin of selected patients requiring depth electrodes studies and rationale for surgical approaches[J]. Epilepsia, 1993, 34:84-96.
[36] Shihabuddin B, Abou-Khalil B, Delbeke D, Fakhoury T. Orbital-frontal epilepsy masquerading as temporal lobe epilepsy-a case report[J]. Seizure, 2001, 10:134-138.
[37] Zhu H, Liu Y, Wu Y, Wang Y, Liu H, Zou Y, Yang K, Wu T, Yang L, Zhang R. Temporal plus epilepsies:electrophysiology studied with interictal magnetoencephalography and intracranial video-EEG monitoring[J]. Seizure, 2013, 22:164-167.
[38] Aghakhani Y, Rosati A, Dubeau F, Olivier A, Andermann F. Patients with temporoparietal ictal symptoms and inferomesial EEG do not benefit from anterior temporal resection[J]. Epilepsia, 2004, 45:230-236.
[39] Falconer M, Driver M, Serafetinides E. Temporal lobe epilepsy due to distant lesions:two cases relieved by operation[J]. Brain, 1962, 85:521-534.
[40] Elwan SA, So NK, Enatsu R, Bingaman WE. Pseudotemporal ictal patterns compared with mesial and neocortical temporal ictal patterns[J]. J Clin Neurophysiol, 2013, 30:238-246.
[41] Wang WW, Wu X. Orbital frontal epilepsy:a type of epilepsy to be further studied[J]. Dian Xian Za Zhi, 2017, 3:50-55[.王薇薇, 吴逊. 眶额区癫痫——有待深入研究的癫痫类型[J]. 癫痫杂志, 2017, 3:50-55.]
[42] Aykut-Bingol C, Bronen RA, Kim JM, Spencer DD, Spencer SS. Surgical outcome in occipital lobe epilepsy:implications for pathophysiology[J]. Ann Neurol, 1998, 44:60-69.
[43] Koubeissi MZ, Jouny CC, Blakeley JO, Bergey GK. Analysis of dynamics and propagation of parietal cingulate seizures with secondary mesial temporal involvement[J]. Epilepsy Behav, 2009, 14:108-112.
[44] Guillem F, N'Kaoua B, Rougier A, Claverie B. Effects of temporal versus temporal plus extra-temporal lobe epilepsies on hippocampal ERPs:physiopathological implications for recognition memory studies in humans[J]. Brain Res Cogn Brain Res, 1995, 2:147-153.
[45] Guillem F, N'Kaoua B, Rougier A, Claverie B. Location of the epileptic zone and its physiopathological effects on memory-related activity of the temporal lobe structures:a study with intracranial event-related potentials[J]. Epilepsia, 1998, 39:928-941.
[46] Labate A, Cerasa A, Aguglia U, Mumoli L, Quattrone A, Gambardella A. Voxel-based morphometry of sporadic epileptic patients with mesiotemporal sclerosis[J]. Epilepsia, 2010, 51:506-510.
[47] Gross DW, Concha L, Beaulieu C. Extratemporal white matter abnormalities in mesial temporal lobe epilepsy demonstrated with diffusion tensor imaging[J]. Epilepsia, 2006, 47:1360-1363.
[48] Avesani M, Giacopuzzi S, Bongiovanni LG, Borelli P, Cerini R, Pozzi Mucelli R, Fiaschi A. EEG-fMRI evaluation of patients with mesial temporal lobe sclerosis[J]. Neuroradiol J, 2014, 27:45-54.
[49] Chassoux F, Semah F, Bouilleret V, Landre E, Devaux B, Turak B, Nataf F, Roux FX. Metabolic changes and electro-clinical patterns in mesio-temporal lobe epilepsy:a correlative study[J]. Brain, 2004, 127(Pt 1):164-174.
[50] Wunderlich G, Schüller MF, Ebner A, Holthausen H, Tuxhorn I, Witte OW, Seitz RJ. Temporal lobe epilepsy with sensory aura:interictal glucose hypometabolism[J]. Epilepsy Res, 2000, 38:139-149.

选择文件类型/文献管理软件名称

选择包含的内容

2 Temporal plus epilepsy定义及其临床特征探究

Temporal plus epilepsy: the conception should be attack great importance and inquiring

RichHTML

PDF

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	佟志勇. 颅内动脉瘤与脑血管重建术[J]. 中国现代神经疾病杂志, 2024, 24(8): 595-598.
[2]	佟志勇. 脑血管重建术历史沿革[J]. 中国现代神经疾病杂志, 2024, 24(8): 599-605.
[3]	金凌骥, 胡俊文, 李寅, 王林. 复杂颅内动脉瘤的颅内-颅内血管搭桥术[J]. 中国现代神经疾病杂志, 2024, 24(8): 606-612.
[4]	刘佩玺, 史源, 朱巍. 血流导向时代颅内全域脑血管搭桥术治疗颅内动脉瘤之应用方略[J]. 中国现代神经疾病杂志, 2024, 24(8): 613-618.
[5]	张峰, 孟凡刚. 帕金森病自主神经功能障碍丘脑底核脑深部电刺激术治疗进展[J]. 中国现代神经疾病杂志, 2024, 24(7): 510-515.
[6]	吴桂智, 田宏. Meige综合征脑深部电刺激术治疗进展[J]. 中国现代神经疾病杂志, 2024, 24(7): 516-521.
[7]	孟凡刚, 张建国. 耳后磨骨槽技术在脑深部电刺激术中的应用[J]. 中国现代神经疾病杂志, 2024, 24(7): 522-524.
[8]	陈琳, 潘华. 功能性震颤的电生理诊断[J]. 中国现代神经疾病杂志, 2024, 24(7): 573-578.
[9]	魏俊吉, 常健博. 深入基层医院普及神经外科重症管理理念[J]. 中国现代神经疾病杂志, 2024, 24(6): 403-406.
[10]	史若琳, 高秀洁, 崔家宁, 邵妍, 谢璐霜, 刘毅. 5-羟色胺与帕金森病非运动症状研究进展[J]. 中国现代神经疾病杂志, 2024, 24(6): 497-501.
[11]	李海峰. 在进入靶向治疗的时代激素仍然是重症肌无力治疗的基础[J]. 中国现代神经疾病杂志, 2024, 24(5): 295-307.
[12]	许鸿嘉, 舒崖清, 王蘋, 李蕃, 许顺良, 邱伟, 马晓宇. 抗水通道蛋白4抗体阳性视神经脊髓炎谱系疾病诊断与治疗进展[J]. 中国现代神经疾病杂志, 2024, 24(5): 308-314.
[13]	黄瑀, 廖金池, 舒崖清. 抗N-甲基-D-天冬氨酸受体脑炎睡眠障碍研究进展[J]. 中国现代神经疾病杂志, 2024, 24(5): 315-319.
[14]	刘彩云, 金涛. 树突状细胞在多发性硬化免疫治疗中的应用[J]. 中国现代神经疾病杂志, 2024, 24(5): 320-330.
[15]	王军成, 赵岳阳, 杨强, 蒯涛, 潘亚文. HMGB1基因调控胶质瘤恶性生物学行为研究进展[J]. 中国现代神经疾病杂志, 2024, 24(5): 391-397.

模态框（Modal）标题

选择文件类型/文献管理软件名称

选择包含的内容

2 Temporal plus epilepsy定义及其临床特征探究

Temporal plus epilepsy: the conception should be attack great importance and inquiring

RichHTML

PDF

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价