中国现代神经疾病杂志 ›› 2025, Vol. 25 ›› Issue (6): 477-482. doi: 10.3969/j.issn.1672-6731.2025.06.004

• 专题综述 • 上一篇    下一篇

2 脑静脉血栓形成抗凝与机械取栓治疗研究进展

郎野, 钟孟飞, 高宗恩*()   

  1. 257034 东营,胜利油田中心医院神经内科
  • 收稿日期:2025-04-14 出版日期:2025-06-25 发布日期:2025-07-04
  • 通讯作者: 高宗恩
  • 基金资助:
    国家自然科学基金资助项目(82171278)

Progress on anticoagulation therapy and mechanical thrombectomy for cerebral venous thrombosis

Ye LANG, Meng-fei ZHONG, Zong-en GAO*()   

  1. Department of Neurology, Shengli Oilfield Central Hospital, Dongying 257034, Shandong, China
  • Received:2025-04-14 Online:2025-06-25 Published:2025-07-04
  • Contact: Zong-en GAO
  • Supported by:
    the National Natural Science Foundation of China(82171278)

摘要:

脑静脉血栓形成是少见但严重的脑血管病,抗凝治疗是首选,静脉窦机械取栓术近年取得显著进步,但临床对机械取栓术的意见并不一致,其与抗凝治疗的桥接、重症脑静脉血栓形成的定义、机械取栓术“时间窗”的界定等问题有待进一步探讨。本文综述脑静脉血栓形成抗凝治疗与机械取栓术治疗进展,并引入机械取栓术“时间窗”概念,以期对未来临床研究和临床实践有所启示。

关键词: 静脉血栓形成, 脑静脉, 抗凝药, 血栓切除术, 综述

Abstract:

Cerebral venous thrombosis (CVT) is a relatively uncommon but serious cerebrovascular disease. Anticoagulation therapy is the preferred treatment. In recent years, significant progress has been made in venous sinus mechanical thrombectomy. However, there is no consensus on mechanical thrombectomy in clinical practice. Issues such as how to bridge thrombectomy with anticoagulation therapy, the definition of severe CVT, and the determination of the mechanical thrombectomy "time window" need further exploration. This paper reviews the progress on anticoagulantion therapy and mechanical thrombectomy for CVT in recent years, and introduces the concept of the "time window" for mechanical thrombectomy, with the aim of providing some inspiration for future clinical research and practice.

Key words: Venous thrombosis, Cerebral veins, Anticoagulants, Thrombectomy, Review