中国现代神经疾病杂志 ›› 2020, Vol. 20 ›› Issue (5): 373-380. doi: 10.3969/j.issn.1672-6731.2020.05.002

• 专论 • 上一篇    下一篇

2 急性大血管闭塞性缺血性卒中血管内治疗的过去、现在和未来

缪中荣, 霍晓川   

  1. 100070 首都医科大学附属北京天坛医院神经介入中心 国家神经系统疾病临床医学研究中心
  • 收稿日期:2020-05-08 出版日期:2020-05-25 发布日期:2020-05-19
  • 通讯作者: 缪中荣,Email:zhongrongm@163.com
  • 基金资助:

    国家重点研发计划项目(项目编号:2016YFC1301501)

Endovascular treatment of acute ischemic stroke with large vessel occlusion: history, present and future

MIAO Zhong-rong, HUO Xiao-chuan   

  1. Department of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University;China National Clinical Research Center for Neurological Diseases, Beijing 100070, China
  • Received:2020-05-08 Online:2020-05-25 Published:2020-05-19
  • Supported by:

    This study was supported by the National Key Research and Development Program of China (No. 2016YFC1301501).

摘要:

2015年N Engl J Med发表5项随机对照临床试验,均证实血管内治疗对急性前循环大血管闭塞性缺血性卒中有效,从而迎来了机械取栓术的"春天",改写了急性缺血性卒中血管内治疗指南,自此急性大血管闭塞性缺血性卒中的救治模式步入新时代,急诊机械取栓术成为急性缺血性卒中治疗的里程碑。2020年是机械取栓术"春天"到来后的5周年,我们通过该项技术获得哪些启发?未来将向何方向发展?通过本综述了解血管内治疗这项革新技术是如何突破黑暗迎来黎明的。

关键词: 卒中, 脑缺血, 动脉闭塞性疾病, 机械溶栓, 综述

Abstract:

Five randomized control clinical trials of N Engl J Med showed the efficacy of endovascular treatment (EVT) of acute ischemic stroke with large vessel occlusion (AIS-LVO) of anterior circulation. The "spring" of mechanical thrombectomy is coming. The international guideline changed and the treatment of AIS-LVO have been entering a new era. Mechanical thrombectomy became the one of milestones in the treatment of ischemic cerebrovascular events. The year of 2020 is the five years' anniversary since the "spring" of thrombectomy. What have we learned and where are we heading? To mark this anniversary year, this review takes you through the evolution of EVT from its tough beginnings to a way through the dark.

Key words: Stroke, Brain ischemia, Arterial occlusive diseases, Mechanical thrombolysis, Review