摘要：

Duchenne 型肌营养不良症是临床最常见的儿童遗传性肌肉病，主要表现为进行性骨骼肌萎缩、肌力逐渐减退、丧失活动能力，运动障碍是Duchenne 型肌营养不良症的核心表现。目前国际上采用的运动功能评价指标主要包括肌力、步行能力、关节活动度和活动能力，但尚未形成统一标准。全面、科学、合理、精确的评价工具是研究Duchenne 型肌营养不良症患者运动功能发育规律的必要条件，为临床选择治疗方法和时机、评价干预方案疗效、制定康复计划等提供依据。

关键词: 肌营养不良, 杜氏, 运动障碍, 综述

Abstract:

Duchenne muscular dystrophy (DMD), clinically featured as progressive skeletal muscle atrophy with gradual loss of muscle strength and activity abilities, is the most common genetic muscular disease in children throughout the world. The core and continuous characteristic of DMD is motor dysfunction. Motor function assessments of DMD are now focusing on muscle strength, walking ability, range of motion and ability of activities, still without unified standards. Confirming the comprehensive, scientific, reasonable and accurate evaluation tools for DMD assessment is the premise of research in motor developmental rules of DMD, which will help to better understand the motor progress of DMD and to supply evidences for choosing treatment methods, confirming timing of intervention, assessing effect of treatments and designing rehabilitation plans.

Key words: Muscular dystrophy, Duchenne, Movement disorders, Review