摘要： 鉴于阿尔茨海默病给现代老龄化社会带来的巨大经济和心理压力，对其进行的基础与临床研究具有重大经济与社会意义。阿尔茨海默病神经影像学计划作为目前国际上开展的最为成功的多中心、跨学科纵向研究，已在阿尔茨海默病研究领域取得了较为突出的成就，本文简单介绍该项研究计划，希望对国内同行有所借鉴。

关键词: 阿尔茨海默病, 磁共振成像, 正电子发射断层显像术, 综述

Abstract: Alzheimer's disease (AD) brought about much pressure in modern aging society both economically and psychologically, so it is meaningful to carry out AD research. Being considered as the most successful multi-center, inter-disciplinary and longitudinal research in AD field, Alzheimer's Disease Neuroimaging Initiative (ADNI) has obtained outstanding achievements. In this review, we attempt to introduce the research plan of ADNI project for reference.

Key words: Alzheimer disease, Magnetic resonance imaging, Positron-emission tomography, Review