Strategies for the prevention and treatment of endometrial injury

doi:10.16352/j.issn.1001-6325.2024.09.1308

Abstract

Abstract: Endometrial injury is the main fact leading to the damage of endometrial basal layer. It is usually caused by traumatic treatment, inflammatory injury, radiation, chemical drug-related injury, and delivery-related diverticulum. The use of hyaluronic acid, decellularized matrix, amniotic membrane, platelet-rich plasma, mesenchymal stem cells (especially scaffold-based therapeutic delivery) has been proved to reduce post-injury scar formation and promote endometrial growth and repair, which provides a new therapeutic strategy for repairing the damaged endometrium with improved tolerability and fertility outcomes.

Key words: endometrial injury, repairment, regeneration, intrauterine adhesion

CLC Number:

711.74

LI Jiaming, YANG Chao, MA Li. Strategies for the prevention and treatment of endometrial injury[J]. Basic & Clinical Medicine, 2024, 44(9): 1308-1313.

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