Basic & Clinical Medicine ›› 2025, Vol. 45 ›› Issue (3): 390-394.doi: 10.16352/j.issn.1001-6325.2025.03.0390

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Platelet-rich plasma combined withmesenchymal stem cells to repair endometrial injury

YE Ke1, WEI Huafang2, SONG Chengwen2*   

  1. 1. Medical School, Wuhan University of Science and Technology, Wuhan 430065;
    2. Department of Obstetrics and Gynecology, General Hospital of Central Theater Command of Chinese PLA, Wuhan 430070, China
  • Received:2024-08-05 Revised:2024-10-30 Published:2025-02-25

Abstract: Endometrial injury disease is a kind of uterine disease of thin endometrium and intrauterine adhesion caused by endometrial basal layer damage. The current clinical use of drug therapy and hysteroscopy surgery can not have good curative effects. Mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) can secrete a variety of active factors to regulate the inflammatory response and immune response of endometrial, promote endometrial proliferation and repair, and there is a mutual promoting effect between the two. Combined use can provide a new idea for the clinical treatment of endometrial injury diseases.

Key words: endometrial injury, platelet-rich plasma, mesenchymal stem cell

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