基础医学与临床 ›› 2023, Vol. 43 ›› Issue (10): 1590-1593.doi: 10.16352/j.issn.1001-6325.2023.10.1590

• 短篇综述 • 上一篇    下一篇

JAK-STAT信号通路与糖尿病并发症的研究进展

余姿漫, 赵炳佳, 杨丹*   

  1. 中国医学科学院 北京协和医学院 北京协和医院 中医科 转化医学中心,北京 100730
  • 收稿日期:2023-07-15 修回日期:2023-08-20 出版日期:2023-10-05 发布日期:2023-10-05
  • 通讯作者: *jsj000jsj@163.com
  • 基金资助:
    国家自然科学基金青年科学基金(82004182)

JAK-STAT signaling pathway and diabetic complications

YU Ziman, ZHAO Bingjia, YANG Dan*   

  1. Department of Traditional Chinese Medicine,Centre for Translational Medicine,Peking Union Medical College Hospital, CAMS & PUMC,Beijing 100730,China
  • Received:2023-07-15 Revised:2023-08-20 Online:2023-10-05 Published:2023-10-05
  • Contact: *jsj000jsj@163.com

摘要: 糖尿病及其并发症严重影响患者的健康和生活质量。近年来,越来越多的研究表明JAK-STAT信号通路在糖尿病并发症的发展和治疗中起着重要作用。本文对JAK-STAT通路与糖尿病及周围神经病变、糖尿病肾病、糖尿病视网膜病变及糖尿病心肌病等方面的研究进展进行了综述。

关键词: JAK-STAT信号通路, 糖尿病, 糖尿病并发症

Abstract: Diabetes mellitus and the complications seriously affect the health and life quality of patients. In recent years, more and more studies have shown that JAK-STAT signaling pathway plays an important role in the development and treatment of diabetic complications. This review focuses on the research progress of JAK-STAT pathway and diabetes, peripheral neuropathy, diabetic nephropathy, diabetic retinopathy and diabetic cardiomyopathy.

Key words: JAK/STAT signaling pathway, diabetes mellitus, diabetic complications

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