糖尿病肾病的生物标志物的研究进展

doi:10.16352/j.issn.1001-6325.2025.04.0546

摘要/Abstract

摘要： 糖尿病肾病(DN)是糖尿病最常见的并发症之一,已成为全球慢性肾病及终末期肾病的主要原因。当前,DN的发病机制尚不完全明确,一直以来,DN的治疗主要是生活管理、降糖、降压等联合治疗,但是依旧不能延缓其进展;因此,DN的早发现、早诊断、早治疗尤为重要,但是目前尚无某个单独指标可以对DN进行早期诊断,所以开发简单、灵敏、高效的生物标志物愈发重要。

关键词: 糖尿病肾病, 生物标志物, 诊断

Abstract: Diabetic nephropathy (DN) is one of the most common complications of diabetes, and has become the main cause of chronic kidney disease and end-stage renal disease worldwide. At present, the pathogenesis of DN is not completely clear. For a long time, the routine treatment of DN is a combination of life management, hypoglycemic, hypotensive with other symptom-based treatment, but its progress cannot be delayed. Therefore, early detection, diagnosis, and treatment of DN are particularly important, but there is currently no single indicator that can be used for early diagnosis of DN. Therefore, the development of simple, sensitive, and efficient biomarkers is becoming increasingly important.

Key words: diabetic nephropathy, biomarkers, diagnosis

中图分类号:

R446.1

赵青青, 程晓亮. 糖尿病肾病的生物标志物的研究进展[J]. 基础医学与临床, 2025, 45(4): 546-550.

ZHAO Qingqing, CHENG Xiaoliang. Research progress on biomarkers of diabetic nephropathy[J]. Basic & Clinical Medicine, 2025, 45(4): 546-550.

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