中国现代神经疾病杂志 ›› 2023, Vol. 23 ›› Issue (11): 1026-1030. doi: 10.3969/j.issn.1672-6731.2023.11.011

• 功能性神经系统疾病 • 上一篇    下一篇

2 功能性肌阵挛诊断与治疗

黄清1, 王刚2,*()   

  1. 1. 210006 南京医科大学附属南京医院 江苏省南京市第一医院神经内科
    2. 200025 上海交通大学医学院附属瑞金医院神经内科
  • 收稿日期:2023-08-13 出版日期:2023-11-25 发布日期:2023-11-30
  • 通讯作者: 王刚
  • 基金资助:
    上海市“医苑新星”杰出青年医师计划项目(2019-72)

Diagnosis and treatment of functional myoclonus

Qing HUANG1, Gang WANG2,*()   

  1. 1. Department of Neurology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu, China
    2. Department of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Received:2023-08-13 Online:2023-11-25 Published:2023-11-30
  • Contact: Gang WANG
  • Supported by:
    Shanghai "Rising Stars of Medical Talent" Outstanding Youth Medical Talents Program(2019-72)

摘要:

功能性肌阵挛属突发性异常运动,是功能性运动障碍常见亚型,临床特点包括突发突止、症状多变、注意分散效应、夹带现象、安慰剂或暗示治疗有效等,神经电生理检测可见较长的爆发持续时间、可变的肌肉募集模式、相对特征性准备电位。诊断主要依靠阳性症状与体征以及神经电生理检测阳性结果。目前尚缺乏一致性治疗意见,推荐心理治疗、物理治疗等多学科诊疗模式。本文综述功能性肌阵挛的临床特征、诊断与鉴别诊断、治疗与预后等,以帮助临床早期准确诊断、及时治疗,改善患者预后。

关键词: 转换障碍, 肌阵挛, 综述

Abstract:

Functional myoclonus is a group of paroxysmal abnormal movements, which is one of the common types of functional movement disorder (FMD). The clinical characteristics include sudden occurrence and sudden arrest, inconsistent symptoms, distraction, entrainment, and placebo or suggestion therapy is effective. Long burst duration, variable muscle recruitment pattern and relatively characteristic bereitschafts potential (BP) can be seen in neuroelectrophysiological examination. The diagnosis is mainly based on the positive clinical symptoms and electrophysiological examination results. At present, there is no unified guideline for treatment, which recommends psychotherapy, physical therapy and multidisciplinary cooperation. This article reviews the clinical characteristics, diagnosis and differential diagnosis, treatment and prognosis of functional myoclonus, in order to help clinical early accurate diagnosis, timely treatment, and improve patient prognosis.

Key words: Conversion disorder, Myoclonus, Review