Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (12): 1955-1959.doi: 10.16352/j.issn.1001-6325.2022.12.1955

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Research progress of transcription factor AP-2 γ in malignant tumors

CHEN Kang, CHENG Fan*   

  1. Department of Urology, Renmin Hospital of Wuhan University, Wuhan 430060, China
  • Received:2021-07-15 Revised:2021-12-17 Online:2022-12-05 Published:2022-11-23
  • Contact: * urology1969@aliyun.com

Abstract: Transcription factor AP-2γ regulates not only the genetic procedures that control the proliferation and differentiation of trophoblast cells during early embryonic development, but also is the key target in the development of breast cancer, lung cancer, testicular cancer, melanoma and pancreatic cancer, thus affecting the occurrence and development of tumors. Therefore, paying attention to the regulatory mechanisms of AP-2γ in the occurrence and development of malignant tumors may provide new ideas for the diagnosis and treatment of tumors.

Key words: transcription factor, AP-2γ, embryonic development, tumor

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