Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (11): 1781-1784.doi: 10.16352/j.issn.1001-6325.2022.11.1781

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Research progress on the role of ferroptosis in the treatment of tumors

WANG Feng-yu, LI Gen, LIN Xiao-yi, YAO Xin-yue, CHEN Yu*   

  1. Hangzhou Medical College,Hangzhou 310051,China
  • Received:2021-07-16 Revised:2021-12-08 Online:2022-11-05 Published:2022-11-01
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Abstract: Ferroptosis, as a regulated and non-apoptotic form of cell death, provides a new research direction for tumor therapy. Ferroptosis is involved in the development of drug resistance in some tumors and also in the treatment process of many tumor therapies, which is a neglected mechanism in tumor therapy. This article will introduce the relationship between ferroptosis and different tumor treatment therapies from the aspects of tumor chemotherapy, tumor radiation therapy and tumor immunotherapy, and summarize the strategies of improving tumor treatment effect by ferroptosis, in order to provide reference for tumor treatment.

Key words: ferroptosis, cell death, tumor

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