基础医学与临床 ›› 2013, Vol. 33 ›› Issue (4): 492-495.
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潘伟,刘世明
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摘要： 自噬是细胞在缺乏营养和能量供应时，部分胞质与细胞器被包裹并被降解为核苷酸、氨基酸及游离脂肪酸等小分子物质，再被重新利用合成大分子或者合成ATP的过程。自噬广泛参与多种疾病的发生，多种心血管疾病的病理过程伴随着心血管系统自噬活性的改变。
关键词: 自噬, 心血管疾病
Abstract: Autophagy was originally defined as the process of sequestration of intracellular components and their subsequent degradation by lysosomal vacuoles. This process is likely the main mechanism involved in the degradation of long-lived proteins and cytoplasmic organelles. Autophagy plays important roles in development of varied diseases.
Key words: autophagy, cardiovascular diseases
中图分类号:
R541
R33
潘伟 刘世明. 自噬与心血管疾病[J]. 基础医学与临床, 2013, 33(4): 492-495.
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