以“肾-三焦”系统诠释间充质干细胞实质

doi:10.16352/j.issn.1001-6325.2023.01.0046

基础医学与临床 ›› 2023, Vol. 43 ›› Issue (1): 46-50.doi: 10.16352/j.issn.1001-6325.2023.01.0046

• 特邀专题：成体干细胞基础创新与临床转化 • 上一篇下一篇

以“肾-三焦”系统诠释间充质干细胞实质

张晓彤¹, 赵月纯¹, 朱镕嘉², 赵春华^2*, 宋坪^1*

1.中国中医科学院广安门医院皮肤科,北京 100053;
2.中国医学科学院基础医学研究所北京协和医学院基础学院组织工程研究中心干细胞新药研发及临床转化研究北京市重点实验室 (BZ0381),北京 100005

收稿日期:2022-07-13 修回日期:2022-10-10 发布日期:2022-12-27
通讯作者: ^*songping@vip.126.com; zhaochunhua@vip.163.com
基金资助:
国家重点研发计划(2018YFA0109800);国家自然科学基金(81573984,81672313)

Interpretation of the essence of mesenchymal stem cells with the “kidney-triple energizers” system

ZHANG Xiaotong¹, ZHAO Yuechun¹, ZHU Rongjia², ZHAO Chunhua^2*, SONG Ping^1*

1. Department of Dermatology,Guang'anmen Hospital,China Academy of Chinese Medical Sciences,Beijing 100053;
2. Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy(BZ0381) /Center of Excellence in Tissue Engineering, Institute of Basic Medical Sciences CAMS, School of Basic Medicine PUMC,Beijing 100005,China

Received:2022-07-13 Revised:2022-10-10 Published:2022-12-27
Contact: ^*songping@vip.126.com; zhaochunhua@vip.163.com

摘要/Abstract

摘要： 肾与三焦在结构与功能上密不可分,故此提出“肾-三焦”可能是间充质干细胞(MSCs)系统的本质,“肾-三焦”是对MSCs系统中医属性的探讨,以肾为本源、三焦为枢机,本文旨在从“肾精为体、三焦为用”的角度诠释MSCs系统的理论内涵,MSCs的形态与分布及发挥功能的物质、途径、功能均可在“肾-三焦”系统中得以体现,并通过中医药理论为指导,运用MSCs的现代研究技术,在COVID-19等难治性疾病的应用中取得了较好的效果,对中西医研究的结合进行了初步探索。

关键词: 间充质干细胞, 肾精, 三焦气化

Abstract: Kidney and triple energizers are inseparable in structure and function. Therefore, it is proposed that “kidney-triple energizers” might be the essence of mesenchymal stem cells (MSCs) system. As a cardinal, this article aims to interpret the theoretical connotation of the mesenchymal stem cell system from the perspective of “the kidney essence is the body and the triple energizers is the function”. It is reflected in the kidney-three energizers system, and guided by the theory of traditional Chinese medicine, the modern technology of MSCs has achieved good results in the application of refractory diseases such as COVID-19, and a preliminary exploration of the integration of Chinese and Western medicine research has been carried out.

Key words: mesenchymal stem cells, kidney essence, triple energizers Qi transformation

中图分类号:

R329.2

张晓彤, 赵月纯, 朱镕嘉, 赵春华, 宋坪. 以“肾-三焦”系统诠释间充质干细胞实质[J]. 基础医学与临床, 2023, 43(1): 46-50.

ZHANG Xiaotong, ZHAO Yuechun, ZHU Rongjia, ZHAO Chunhua, SONG Ping. Interpretation of the essence of mesenchymal stem cells with the “kidney-triple energizers” system[J]. Basic & Clinical Medicine, 2023, 43(1): 46-50.

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以“肾-三焦”系统诠释间充质干细胞实质

Interpretation of the essence of mesenchymal stem cells with the “kidney-triple energizers” system

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