Research progress on biomarkers of early diagnosis and prognosis of cerebral small vessel disease

doi:10.3969/j.issn.1672-6731.2023.11.005

Abstract

Abstract:

Cerebral small vessel disease (CSVD) is an important risk factor for stroke, dementia and death, which seriously endangers the health and quality of life of the elderly. The onset of CSVD is insidious and there is a lack of early diagnosis methods and interventions, so the search for markers that can provide early warning of CSVD and prognosis assessment is very important for the prevention and treatment of the disease. This article reviews imaging and laboratory biomarkers for early diagnosis and prognosis of CSVD, in order to provide new ideas for the formulation of prevention, diagnosis and treatment strategies related to the disease.

Key words: Cerebral small vessel diseases, Magnetic resonance imaging, Biomarkers, Review

摘要：

脑小血管病是脑卒中、痴呆和死亡的重要危险因素，严重危害老年人生命健康和生活质量。脑小血管病起病隐匿，缺乏早期诊断方法及干预措施，探究脑小血管病早期诊断及预后评估标志物对疾病的预防与治疗至关重要。本文综述脑小血管病早期诊断及预后评估的影像学和实验室标志物，以为脑小血管病预防、诊断及治疗策略的制定提供新的思路。

关键词: 大脑小血管疾病, 磁共振成像, 生物标记, 综述

Li-mo-ran TANG, Yun XU. Research progress on biomarkers of early diagnosis and prognosis of cerebral small vessel disease[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2023, 23(11): 978-985.

唐李默然, 徐运. 脑小血管病早期诊断及预后评估生物学标志物研究进展[J]. 中国现代神经疾病杂志, 2023, 23(11): 978-985.

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