Chinese Journal of Contemporary Neurology and Neurosurgery ›› 2019, Vol. 19 ›› Issue (10): 765-765. doi: 10.3969/j.issn.1672-6731.2019.10.017
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YAN Xiao-ling
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阎晓玲
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摘要:
中枢神经系统分化的软骨肉瘤临床十分罕见,多起源于颅底,可发生于任何年龄段,中年男性比例稍高。组织学形态,肿瘤组织呈分叶状,偶见钙化,细胞大小、形状不一,呈卵圆形或多角形,轻度异型性,胞核较大、浓染(图 1),常见双核细胞;间质黏液变性和软骨样基质液化是软骨肉瘤的常见表现;可见坏死和核分裂象。免疫组织化学染色,肿瘤细胞胞质和胞核均表达S-100蛋白(S-100),胞质表达 D2-40(图2)和异柠檬酸脱氢酶1(IDH1)R132H。
YAN Xiao-ling. Chondrosarcoma[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2019, 19(10): 765-765.
阎晓玲. 软骨肉瘤[J]. 中国现代神经疾病杂志, 2019, 19(10): 765-765.
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https://journal11.magtechjournal.com/cjcnn/EN/Y2019/V19/I10/765