Abstract: Objective  The dorsal root entry zone (DREZ) is a hyperactive focus in neuropathic pain (NP) syndromes, and DREZotomy has been used in selective cases of NP. This study aims to investigate the therapeutic effect of microsurgical DREZotomy in chronic pain due to spinal cord and cauda equina injuries. Methods  Two patients suffered with chronic pain due to spinal cord and cauda equina injuries were treated with microsurgical DREZotomy, and postoperative therapeutic effect and complications were observed.  Results  One patient had great pain, and the pain was alleviated 2 weeks after surgery, while carbamazepine (300 mg/d) was administered continously. Another patient was completely free of pain 2 weeks after surgery, and no recurrence occurred during 3-year follow up. No severe complications were found in the 2 patients.  Conclusion  Microsurgical DREZotomy is an effective approach in treating chronic pain due to spinal cord and cauda equina injuries.

Key words: Pain, Spinal cord injuries, Caude equina, Neurosurgical procedures

摘要： 目的 探讨脊髓背根入髓区切开术治疗脊髓和马尾神经损伤后慢性疼痛之疗效。方法 采用脊髓背根入髓区切开术治疗2 例脊髓和马尾神经损伤后慢性疼痛患者，观察术后疗效及并发症。结果 术后2 周时1 例症状明显减轻但仍需口服卡马西平（300 mg/d）、1 例症状完全消失且随访3 年6 个月未出现疼痛，术后无一例发生严重并发症。结论 脊髓背根入髓区切开术是治疗脊髓和马尾神经损伤后慢性疼痛的有效方法。

关键词: 疼痛, 脊髓损伤, 马尾, 神经外科手术