中国现代神经疾病杂志 ›› 2026, Vol. 26 ›› Issue (1): 65-68. doi: 10.3969/j.issn.1672-6731.2026.01.009

• 神经调控前沿理论与临床转化 • 上一篇    下一篇

2 脑深部电刺激术在脑卒中后运动功能障碍中应用进展

魏新明, 冯珂珂   

  1. 300350 天津医科大学附属环湖医院神经外科
  • 收稿日期:2025-11-21 发布日期:2026-01-29
  • 通讯作者: 冯珂珂,Email:fengke1976@163.com

Progress on the application of deep brain stimulation in motor dysfunction after stroke

WEI Xin-ming, FENG Ke-ke   

  1. Department of Neurosurgery, Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin 300350, China
  • Received:2025-11-21 Published:2026-01-29

摘要: 脑卒中患者常遗留运动功能障碍,影响生活质量,亟待有效的康复治疗手段。脑深部电刺激术作为一种成熟的神经调控技术,近年在促进脑卒中后运动功能康复领域展现出巨大潜力。本文阐述脑深部电刺激术治疗脑卒中后运动功能障碍的解剖学和病理生理学基础,综述小脑齿状核脑深部电刺激术的临床前和临床研究进展,以期为临床实践提供科学依据及新的治疗视角。

关键词: 卒中, 运动障碍, 深部脑刺激法, 小脑核, 综述

Abstract: Stroke is one of the main causes of adult disability. Patients after stroke often suffer from motor dysfunction, which affects their quality of life and requires effective treatment methods. Deep brain stimulation (DBS), as a mature neuromodulation technique, has shown significant potential in promoting the recovery of motor function after stroke in recent years. This article systematically reviews the mechanism of action of DBS in the treatment of motor dysfunction after stroke, especially summarizing the preclinical and clinical studies on the dentate nucleus of the cerebellum deep brain stimulation (DN-DBS), to provide scientific evidence and new therapeutic perspectives for clinical practice.

Key words: Stroke, Motor disorders, Deep brain stimulation, Cerebellar nuclei, Review

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