儿童垂体腺瘤诊断与治疗进展

doi:10.3969/j.issn.1672-6731.2024.09.005

中国现代神经疾病杂志 ›› 2024, Vol. 24 ›› Issue (9): 717-722. doi: 10.3969/j.issn.1672-6731.2024.09.005

2 儿童垂体腺瘤诊断与治疗进展

王传伟¹, 杜国然², 王延召¹, 祝绍磊³, 张斌⁴, 宫杰¹^,*()

1. 250012 济南, 山东大学齐鲁医院神经外科
2. 253700 山东省德州市庆云县人民医院神经外科
3. 265200 山东省烟台市莱阳中心医院神经外科
4. 277599 枣庄, 山东省滕州市中心人民医院神经外科

收稿日期:2024-08-12 出版日期:2024-09-25 发布日期:2024-10-10
通讯作者: 宫杰
作者简介:
王传伟与杜国然对本文有同等贡献

WANG Chuan-wei and DU Guo-ran contributed equally to the article
基金资助:
齐鲁卫生与健康杰出青年人才

Progress on diagnosis and treatment of pituitary adenoma in children

Chuan-wei WANG¹, Guo-ran DU², Yan-zhao WANG¹, Shao-lei ZHU³, Bin ZHANG⁴, Jie GONG¹^,*()

1. Department of Neurosurgery, Qilu Hospital of Shandong University, Ji'nan 250012, Shandong, China
2. Department of Neurosurgery, Qingyun County People's Hospital, Dezhou 253700, Shandong, China
3. Department of Neurosurgery, Yantai City Laiyang Center Hospital, Yantai 265200, Shandong, China
4. Department of Neurosurgery, Tengzhou Central People's Hospital, Zaozhuang 277599, Shandong, China

Received:2024-08-12 Online:2024-09-25 Published:2024-10-10
Contact: Jie GONG
Supported by:
Qilu Hygiene and Health Outstanding Youth Project

摘要/Abstract

摘要：

垂体腺瘤为颅内良性肿瘤，常见于成人、偶见于儿童，根据是否存在激素分泌异常分为功能性和无功能性腺瘤，主要表现为内分泌功能紊乱、视觉障碍、颅内高压等。儿童垂体腺瘤发病率低，但对儿童生理和心理的影响较明显，临床诊疗具有其独特性，鉴别诊断较成人更复杂，如内分泌症状多见、副鼻窦气化不良、经鼻蝶手术对发育期儿童的影响、药物和放射治疗的儿童化及个体化、术后内分泌调节及后续生长发育等。本文对儿童垂体腺瘤近年临床研究进展进行综述，为神经外科医师诊断与治疗儿童垂体腺瘤提供参考。

关键词: 垂体肿瘤, 垂体激素类, 儿童, 综述

Abstract:

Pituitary adenoma is a benign intracranial tumor, commonly found in adults and occasionally in children. Pituitary adenoma is classified into secretory and non-secretory adenoma based on whether there is abnormal hormone secretion. The main manifestations include endocrine system abnormalities, visual disturbance and symptoms of intracranial hypertension. Although the incidence rate of pituitary adenoma in children is low, its physiological and psychological impact on children is obvious, diagnostic and therapeutic process is unique, and it has some characteristics, more complicated differential diagnosis than adults, such as more endocrine symptoms, poor paranasal sinus gasification, the impact of transnasal surgery on developing children, drug therapy and radiotherapy for children and individualization, postoperative endocrine regulation and subsequent development problems, etc.. Therefore, it is necessary to discuss pituitary adenoma in children independently from adults. This article reviews the clinical research progress of pediatric pituitary adenoma in recent years.

Key words: Pituitary neoplasms, Pituitary hormones, Child, Review

王传伟, 杜国然, 王延召, 祝绍磊, 张斌, 宫杰. 儿童垂体腺瘤诊断与治疗进展[J]. 中国现代神经疾病杂志, 2024, 24(9): 717-722.

Chuan-wei WANG, Guo-ran DU, Yan-zhao WANG, Shao-lei ZHU, Bin ZHANG, Jie GONG. Progress on diagnosis and treatment of pituitary adenoma in children[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2024, 24(9): 717-722.

https://journal11.magtechjournal.com/cjcnn/CN/Y2024/V24/I9/717

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