中国现代神经疾病杂志 ›› 2022, Vol. 22 ›› Issue (11): 927-931. doi: 10.3969/j.issn.1672-6731.2022.11.003

• 专题综述 • 上一篇    下一篇

2 迷走神经刺激术治疗脑卒中后上肢运动障碍进展

屈超华1, 王婷婷1,2, 屈云1,2   

  1. 1. 610041 成都, 四川大学华西医院康复医学中心;
    2. 610041 成都, 康复医学四川省重点实验室 华西康复医学研究所神经康复研究室
  • 收稿日期:2022-11-20 出版日期:2022-11-25 发布日期:2022-12-09
  • 通讯作者: 屈云,Email:dr_yunqu@163.com
  • 基金资助:
    四川省科技计划项目(项目编号:2021YJ0184)

Research progress on vagus nerve stimulation for post-stroke upper limb motor disorders

QU Chao-hua1, WANG Ting-ting1,2, QU Yun1,2   

  1. 1. Department of Rehabilitation Medicine, Sichuan University, Chengdu 610041, Sichuan, China;
    2. Key Laboratory of Rehabilitation Medicine in Sichuan Province, Research Laboratory of Neurorehabilitation, Research Institute of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China
  • Received:2022-11-20 Online:2022-11-25 Published:2022-12-09
  • Supported by:
    This study was supported by Science and Technology Project in Sichuan (No.2021YJ0184).

摘要: 迷走神经刺激术是一种新兴的神经调控技术,业已应用于脑卒中后康复治疗。近年来,迷走神经刺激术结合康复训练用于改善脑卒中患者上肢运动功能初见疗效,但相关作用机制及最佳刺激参数仍未明确。本文拟对迷走神经刺激术结合康复训练治疗脑卒中后上肢运动障碍的基础与临床研究证据进行总结,并探讨可能的作用机制及最佳刺激参数,以为脑卒中后上肢运动障碍的康复治疗提供新的思路。

关键词: 卒中, 运动障碍, 上肢, 迷走神经刺激术, 康复, 综述

Abstract: Vagus nerve stimulation (VNS) is an emerging neuromodulation therapy that has been used in post-stroke rehabilitation. In recent years, VNS combined with rehabilitation has been used to improve upper limb motor function in stroke patients, but the mechanisms and optimal stimulation parameters are still unclear. In this paper, we summarize the evidence from basic and clinical studies of VNS combined with rehabilitation for post-stroke upper limb motor disorders, and discuss the possible mechanisms and optimal stimulation parameters, provide new ideas for the rehabilitation of post-stroke upper limb motor disorders.

Key words: Stroke, Motor disorders, Upper extremity, Vagus nerve stimulation, Rehabilitation, Review