中国现代神经疾病杂志 ›› 2014, Vol. 14 ›› Issue (3): 176-180. doi: 10.3969/j.issn.1672-6731.2014.03.006

• 专题讲座 • 上一篇    下一篇

2 阿尔茨海默病神经影像学研究进展

李坤成   

  1. 100053 北京,首都医科大学宣武医院放射科 磁共振成像脑信息学北京市重点实验室 神经变性病教育部重点实验室
  • 出版日期:2014-03-25 发布日期:2014-03-21
  • 通讯作者: 李坤成 (Email: cjr.likuncheng@vip.163.com)
  • 基金资助:

    国家自然科学基金资助项目(项目编号:81141018);北京市科技计划重点项目(项目编号:Z101107052210002)

Progress of neuroimaging research on Alzheimer's disease

LI Kun-cheng   

  1. Department of Radiology, Xuanwu Hospital, Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Key Laboratory for Neurodegenerative Diseases of Ministry of Education, Capital Medical University, Beijing 100053, China
  • Online:2014-03-25 Published:2014-03-21
  • Contact: LI Kun-cheng (Email: cjr.likuncheng@vip.163.com)
  • Supported by:

    This study was supported by National Natural Science Foundation of China (No. 81141018) and Key Project of Beijing Science and Technology Plan (No. Z101107052210002).

摘要:

阿尔茨海默病是临床最常见的老年期痴呆类型。在当今老龄化社会中,阿尔茨海默病发病率呈逐年升高之趋势,且治疗效果较差,给社会带来巨大的经济负担。建立在早期诊断基础上的临床干预可以延缓阿尔茨海默病进展,改善患者预后,本文拟对阿尔茨海默病早期诊断的神经影像学进展进行综述。

关键词: 阿尔茨海默病, 认知障碍, 磁共振成像, 正电子发射断层显像术, 综述

Abstract:

Alzheimer's disease is the most common neurodegenerative disease which gives rise to senile dementia. High morbidity and poor efficacy of Alzheimer's disease have brought about much pressure to the aging society. However, based on early diagnosis, early clinical intervention may slow down the progression of disease and improve its prognosis. In this review, we attempt to introduce the progress of early neuroimaging diagnosis of Alzheimer's disease.

Key words: Alzheimer disease, Cognition disorders, Magnetic resonance imaging, Positron-emission tomography, Review