摘要：

苯巴比妥作为传统抗癫痫药物在临床应用已逾百年，至今仍在世界范围内广泛应用。作为世界卫生组织推荐的发展中国家治疗和控制癫痫发作的一线药物，苯巴比妥能够有效缩小治疗缺口。本文对苯巴比妥在世界范围内的应用情况、疗效及其相关药物不良反应的研究进展进行概述。

关键词: 苯巴比妥, 癫痫, 综述

Abstract:

As a classic antiepileptic drug (AED), phenobarbital has been used in clinic for more than 100 years and is available in the majority of countries in the world. Accepted as the drug of choice for controlling seizures in developing countries by World Health Organization (WHO), phenobarbital can effectively lessen the treatment gap. In this paper, the utilization of phenobarbital around the world, and its curative effect and adverse drug reaction were reviewed.

Key words: Phenobarbital, Epilepsy, Review