摘要： 阿司匹林对脑卒中二级预防的效果已经确定，但其在脑卒中一级预防中的获益和风险仍存在较大争议。基于现有的临床证据，仅部分人群从阿司匹林一级预防措施中获益，本文结合相关脑卒中一级预防指南和主要文献，就阿司匹林在脑卒中一级预防中的应用依据、作用机制、适用人群及风险评价等简要概述。

关键词: 卒中, 一级预防, 阿司匹林, 综述

Abstract: Aspirin is effective in the second prevention for stroke. However, its benefits and risk in the primary prevention are disputed. Based on current clinical observation, only part of the population could benefit from aspirin in the primary prevention. This article focuses on the evidence, mechanism, applicable people and risk assessment in the application of aspirin based on guidelines and important articles for the primary prevention of stroke.

Key words: Stroke, Primary prevention, Aspirin, Review