Basic & Clinical Medicine ›› 2015, Vol. 35 ›› Issue (6): 842-845.

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Advances of miRNA in early diagnosis and prognosis of cervical cancer

  

  • Received:2014-11-24 Revised:2015-01-21 Online:2015-06-05 Published:2015-05-27

Abstract: MicroRNA play an important role in the process of cervical cancer incidence, invasion, metastasis and recurrence, and closely related to its prognosis. The abnormal expression of miRNAs in cervical cancer patients’s serum can be used as a noninvasive diagnostic and prognostic biomarkers.Based on studies of serum microRNAs, the early presence of cervical cancer can be detected, reduce tumor metastasis and recurrence, search for therapeutic targets, tumor recurrence are reduced, and find targets and breakthrough in diagnosis and treatment of cervical cancer.

Key words: cervical cancer, miRNA, early diagnosis, prognosis

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