Research progress on the role of NAD+ metabolism in cell function and related-diseases

doi:10.16352/j.issn.1001-6325.2022.02.014

Abstract

Abstract: Nicotinamide adenine dinucleotide (NAD⁺) is an important coregulatory factor in cells. The metabolic disorder of NAD⁺ is closely related to the damage of cell function, physiological changes and the occurrence and development of diseases. The decrease of NAD⁺ level is accompanied by the occurrence of metabolic and age-related diseases such as aging, hearing impairment and cardiac damage.Therefore, it provides a new idea for the treatment of these diseases by supplementing and restoring the level of NAD⁺.

Key words: nicotinamide adenine dinucleotide, metabolism, aging, hearing impairment, cardiac damage

CLC Number:

HE Sheng-mei, ZHAO Hou-yu. Research progress on the role of NAD⁺ metabolism in cell function and related-diseases[J]. Basic & Clinical Medicine, 2022, 42(2): 306-310.

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Research progress on the role of NAD⁺ metabolism in cell function and related-diseases

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