基础医学与临床 ›› 2025, Vol. 45 ›› Issue (12): 1692-1696.doi: 10.16352/j.issn.1001-6325.2025.12.1692

• 专家观点 • 上一篇    

针对慢性疾病的干细胞与整合医学体系的构想

赵春华*, 姬云飞, 王世华, 安星燕   

  1. 中国医学科学院基础医学研究所 北京协和医学院基础学院 组织工程研究中心, 北京 100005
  • 收稿日期:2025-09-20 修回日期:2025-10-20 出版日期:2025-12-05 发布日期:2025-11-25
  • 通讯作者: *zhaochunhua@ibms.pumc.edu.cn
  • 基金资助:
    国家自然科学基金(82474345,82471598);中国医学科学院医学与健康科技创新工程(2022-I2M-1-012);高等学校学科创新引智计划(B18007);全国重点实验室专项经费(2060204)

A stem cell and integrative medicine system for chronic diseases: a conceptual framework

ZHAO Chunhua*, JI Yunfei, WANG Shihua, AN Xingyan   

  1. Center for Excellence in Tissue Engineering, Institute of Basic Medical Sciences CAMS, School of Basic Medicine PUMC, Beijing 100005, China
  • Received:2025-09-20 Revised:2025-10-20 Online:2025-12-05 Published:2025-11-25
  • Contact: *zhaochunhua@ibms.pumc.edu.cn

摘要: 本文围绕慢性疾病根源性干预的临床需求,系统阐述了“量子预测-中西医防控-干细胞修复”三位一体的整合医学理论体系及其转化路径。针对糖尿病等复杂慢性病多靶点、系统性的病理特征,研究融合干细胞技术、中医整体观、西医循证医学及量子生物学前沿概念等多学科优势,旨在构建一个“病证结合、宏观微观互参”的全新诊疗范式, 为慢性病管理带来新的思维模式。在理论层面,提出以亚全能干细胞为核心、中西医协同的细胞和微环境重塑策略;在实践层面,通过标准化工艺、临床前验证、多中心临床试验及智能健康管理系统,实现从分子预警、动态防控到组织修复的系统化整合。

关键词: 干细胞治疗, 慢性病, 整合医学

Abstract: This article focuses on the clinical need for curative interventions in chronic diseases. It proposes an integrated medical framework that combines “quantum prediction, prevention and control through Traditional Chinese and Western Medicine, and stem cell repair” and details its path to clinical application. To address the complex, multi-target pathology of diseases like diabetes, this research integrates multiple disciplines: stem cell technology, the holistic philosophy of Traditional Chinese Medicine(TCM), the evidence-based rigor of Western Medicine, and the cutting-edge concepts of quantum biology. The goal is to create a new diagnostic and therapeutic model that synthesizes disease and syndrome classification while bridging macro and micro perspectives, ultimately driving breakthroughs in chronic disease management.Theoretically, the study proposes a strategy to rejuvenate cells and remodel the microenvironment using pluripotent stem cells combined with synergistic TCM-Western Medicine approaches. Practically, it establishes a seamless system—from molecular early-warning and dynamic prevention to tissue repair—supported by standardized protocols, preclinical validation, multi-center clinical trials, and an intelligent health management platform.

Key words: stem cell therapy, chronic diseases, integrated medicine

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