基础医学与临床 ›› 2024, Vol. 44 ›› Issue (4): 428-433.doi: 10.16352/j.issn.1001-6325.2024.04.0428

• 特邀专题:妊娠期营养 • 上一篇    下一篇

锶与妊娠及妊娠期疾病的研究进展

王瑞, 李蕊, 李运龙, 张玉萍, 于康*, 刘燕萍*   

  1. 中国医学科学院 北京协和医学院 北京协和医院 临床营养科,北京 100730
  • 收稿日期:2024-02-26 修回日期:2024-03-01 出版日期:2024-04-05 发布日期:2024-03-25
  • 通讯作者: *liuyp1227@vip.sina.com; yuk1997@sina.com
  • 基金资助:
    中央高水平医院临床研究业务项目(2022-PUMCH-B-055);国家卫生健康委员会微量元素与营养重点实验室开放项目(Wlkfz202203);中国营养学会研究基金-振东基金(CNS-ZD2021-123)

Research progress of strontium and pregnancy and pregnancy diseases

WANG Rui, LI Rui, LI Yunlong, ZHANG Yuping, YU Kang*, LIU Yanping*   

  1. Department of Clinical Nutrition, Peking Union Medical College Hospital, CAMS& PUMC, Beijing 100730,China
  • Received:2024-02-26 Revised:2024-03-01 Online:2024-04-05 Published:2024-03-25
  • Contact: *liuyp1227@vip.sina.com; yuk1997@sina.com

摘要: 锶(Sr)是一种天然存在的微量元素,主要存在于人类骨骼系统中。近年来,锶对骨骼和心血管健康的潜在影响引起了人们的极大关注,尤其是在怀孕期间,矿物质代谢的变化可能会影响母亲和胎儿的健康。这篇综述评估了目前对锶作为妊娠期营养物质的作用,对母体健康和胎儿发育的影响以及与妊娠并发症(如先兆子痫、妊娠高血压和哺乳期骨质疏松症)的潜在相关性,并总结了锶缺乏、过量和补充的可能影响,为制定产前营养补充指南提供参考信息。

关键词: 锶, 妊娠, 氧化应激, 妊娠期骨质疏松

Abstract: Strontium(Sr) is a trace element naturally found in the human skeletal system. In recent years, the potential impact of strontium on bone and cardiovascular health has called significant attention, particularly during pregnancy, when alterations in mineral metabolism may affect the health of both the mother and the fetus. This comprehensive review assesses the current understanding of the role of strontium as a nutritional substance during pregnancy, its effects on maternal health and fetal development, and its potential associations with pregnancy complications such as preeclampsia, gestational hypertension, and lactation-induced osteoporosis. The review also summarizes the possible effects of strontium deficiency, excess, and supplementation, and provides information for developing prenatal nutrition supplementation guideline.

Key words: strontium, pregnancy, oxidative stress, gestational osteoporosis

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