中国现代神经疾病杂志 ›› 2021, Vol. 21 ›› Issue (9): 769-782. doi: 10.3969/j.issn.1672-6731.2021.09.007

• 2021年WHO中枢神经系统肿瘤分类(第五版)解读 • 上一篇    下一篇

2 2021年世界卫生组织中枢神经系统肿瘤分类(第五版)新增肿瘤介绍

李智   

  1. 510080 广州,广东省人民医院病理科
  • 收稿日期:2021-08-24 发布日期:2021-10-09
  • 作者简介:李智,Email:lizhi20203939@163.com

Introduction of newly identified tumor types in the 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition)

LI Zhi   

  1. Department of Pathology, Guangdong Provincial People's Hospital, Guangzhou 510080, Guangdong, China
  • Received:2021-08-24 Published:2021-10-09
  • Contact: 10.3969/j.issn.1672-6731.2021.09.007

摘要:

2021年世界卫生组织中枢神经系统肿瘤分类(第五版,简称新版肿瘤分类)着重推进分子病理诊断在中枢神经系统肿瘤分类中的作用,并根据肿瘤组织学形态和分子遗传学特征新增22个肿瘤类型或亚型,反映出对肿瘤临床病理学和分子遗传学的最新认知。本文拟简要介绍新版肿瘤分类中具有组织学形态特征的新增肿瘤,以加强对其生物学行为的理解和提高病理诊断的准确性,使患者获益。

关键词: 中枢神经系统肿瘤, 指南, 世界卫生组织, 神经病理学, 病理学, 分子, 综述

Abstract:

The 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition) focused on promoting the molecular pathological diagnosis in the role of the central nervous system tumor classification. According to the tumor histopathological morphology and genetic features, the new edition tumors classification added 22 tumor types or subtypes, which reflects the latest recognition of tumor clinical pathology and molecular genetics. In this paper, we will briefly introduce the new tumors with specific histopathological features in new edition tumors classification, with the purpose of understanding the biological behavior of these tumors and improving the accuracy of diagnosis, so as to benefit patients.

Key words: Central nervous system neoplasms, Guidelines, World Health Organization, Neuropathology, Pathology, molecular, Review