摘要：

阿尔茨海默病是以记忆损害为早期表现和特征的缓慢进展的神经退行性疾病，为最常见的痴呆类型。发病率逐年升高，发病机制复杂，药物治疗效果欠佳，而运动锻炼、认知训练、生活方式干预、心理治疗和音乐疗法等非药物治疗可以通过多种途径减缓阿尔茨海默病的发生发展。因此，应重视早期阿尔茨海默病的非药物治疗，联合药物治疗和多种非药物治疗方法进行多靶点干预，以期最大化改善患者临床症状。

关键词: 阿尔茨海默病, 体育运动, 认知疗法, 健康生活方式, 心理疗法, 综述

Abstract:

Alzheimer's disease (AD) is a neurodegeneration disease, characterized by progressive decline of global cognition with memory impairment as its early and the most prominent manifestation. AD is the most common type of dementia. The prevalence of AD is increasing every year. The mechanisms of AD are complicated and there are limited effects of drug therapies. Non-pharmacological interventions including physical activity, cognitive training, life-style treatments, psychological and music therapies, etc. could delay the process of AD through multiple ways. Non-pharmacological interventions of early AD should be emphasized, and we should combine various pharmacological and non-pharmacological interventions together, which will maximum optimize the effects of treatments for clinical symptoms.

Key words: Alzheimer disease, Sports, Cognitive therapy, Healthy lifestyle, Psychotherapy, Review