中国现代神经疾病杂志 ›› 2021, Vol. 21 ›› Issue (9): 809-816. doi: 10.3969/j.issn.1672-6731.2021.09.011

• 2021年WHO中枢神经系统肿瘤分类(第五版)解读 • 上一篇    下一篇

2 2021年世界卫生组织中枢神经系统肿瘤分类(第五版)室管膜肿瘤分类解读

潘灏1, 杨学军2, 李志勇3, 黄广龙3, 漆松涛3   

  1. 1 210002 南京大学医学院附属金陵医院 东部战区总医院神经外科;
    2 102218 清华大学附属北京清华长庚医院神经外科;
    3 510515 广州, 南方医科大学南方医院神经外科
  • 收稿日期:2021-08-30 发布日期:2021-10-09
  • 通讯作者: 杨学军,Email:ydenny@126.com

Interpretation on ependymal tumors in the 2021 WHO Classification of Tumors of the Central Nervous System (fifth edition)

PAN Hao1, YANG Xue-jun2, LI Zhi-yong3, HUANG Guang-long3, QI Song-tao3   

  1. 1 Department of Neurosurgery, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, Jiangsu, China;
    2 Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, Affiliated Hospital of Tsinghua University, Beijing 102218, China;
    3 Department of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong, China
  • Received:2021-08-30 Published:2021-10-09
  • Contact: 10.3969/j.issn.1672-6731.2021.09.011

摘要:

2021年,世界卫生组织(WHO)发布第五版中枢神经系统肿瘤分类(简称新版肿瘤分类),与2016年WHO中枢神经系统肿瘤分类第四版修订版相比,对室管膜肿瘤进行诸多更新,按解剖部位分类、增加数个新的分子亚型、调整黏液乳头状型室管膜瘤分级、删除室管膜瘤分类等。本文结合近年相关文献,对新版肿瘤分类的更新进行解读,以期加深对室管膜肿瘤的认识,更好地指导临床。

关键词: 室管膜瘤, 指南, 世界卫生组织, 病理学, 分子, 综述

Abstract:

In 2021, the WHO released the Classification Tumors of the Central Nervous System (fifth edition). Compared with the revised version of the fourth edition of the WHO Classification of Tumor of the Central Nervous System in 2016, classification of ependymal tumors has many adjustments. Ependymal tumors are classified according to anatomical sites. Several new molecular subtypes are added. Myxopapillary ependymoma is adjusted to WHO grade 2 instead of grade 1. Definition of the ependymoma is deleted. Combined with the relevant literature in recent years, we interpret the updates in this new edition tumors classification about ependymal tumors in order to deepen the understanding of ependymal tumors and standardize the clinical practice.

Key words: Ependymoma, Guidelines, World Health Organization, Pathology, molecular, Review