摘要：

分别采用抑郁自评量表和36 条简明健康状况调查表评价100 例原发性帕金森病患者的抑郁障碍和生活质量，结果显示，除生理职能差异无统计学意义外（P > 0.05），生理功能（P = 0.001）、情感（P = 0.000）、社会功能（P = 0.007）、躯体疼痛（P = 0.000）、精力（P = 0.000）、精神健康（P = 0.000）、一般健康（P = 0.004）和总评分（P = 0.000）差异均有统计学意义。提示抑郁障碍可以降低帕金森病患者的生活质量。

关键词: 帕金森病, 抑郁, 生活质量

Abstract:

To investigate depressive symptoms and quality of life in 100 patients with idiopathic Parkinson's disease (PD) by using Self-Rating Depression Scale (SDS) and Medical Outcomes Study 36-Item Short-Form Healthy Survey (SF-36). Physiological role had no significant difference (P > 0.05), while physiological function (P = 0.001), emotions (P = 0.000), social function (P = 0.007), body pain (P = 0.000), energy (P = 0.000), mental health (P = 0.000), general health (P = 0.004) and total score (P = 0.000) had statistically significant difference in PD patients with different degrees of depressive symptoms. The study indicates that depressive symptoms may impact the quality of life in PD patients.

Key words: Parkinson disease, Depression, Quality of life