基础医学与临床 ›› 2010, Vol. 30 ›› Issue (12): 1349-1351.

• 短篇综述 • 上一篇    下一篇

干扰肌动蛋白细胞骨架对NF-κB活性影响的研究进展

郭维康,刘文虎,张东亮   

  1. 首都医科大学附属北京友谊医院
  • 收稿日期:2010-06-29 修回日期:2010-07-31 出版日期:2010-12-05 发布日期:2010-12-05
  • 通讯作者: 刘文虎

Effect of perturbating F-actin cytoskelecton on NF-κB activation

GUO Wei-kang ,LIU Wen-hu ,ZHANG Dong-liang   

  1. Bejing Friendship Hospital,Capital Medical University
  • Received:2010-06-29 Revised:2010-07-31 Online:2010-12-05 Published:2010-12-05
  • Contact: LIU Wen-hu

摘要: 本文介绍了肌动蛋白细胞骨架的构成、功能以及NF-κB信号传导通路的激活途径,重点阐述了通过改变肌动蛋白细胞骨架途径来影响NF-κB活性的机制。

关键词: NF-kappa B, 肌动蛋白细胞骨架, 细胞骨架干扰剂

Abstract: The activation of the NF-κappa B signal transduction and the construction of the actin- cytoskeleton are simply introduced. The mechanism that NF-κappa B can be influenced through perturbation of the F-actin cytoskeleton is emphasized and prospect of this research is also introduced.