基础医学与临床 ›› 2019, Vol. 39 ›› Issue (7): 1040-1044.

• 临床研究 • 上一篇    下一篇

颞叶海绵状血管瘤继发癫痫的手术治疗

刘琦1,郭毅2,郭金竹3,窦万臣2   

  1. 1. 中国医学科学院北京协和医院
    2. 中国医学科学院 北京协和医学院 北京协和医院 神经外科
    3. 北京协和医院
  • 收稿日期:2018-08-06 修回日期:2018-11-30 出版日期:2019-07-05 发布日期:2019-07-02
  • 通讯作者: 窦万臣 E-mail:douwanchen@yahoo.com.cn

Surgical strategy for temporal lobe epilepsy caused by cavernous malformation

  • Received:2018-08-06 Revised:2018-11-30 Online:2019-07-05 Published:2019-07-02

摘要: 目的 探讨以癫痫为临床表现的颞叶海绵状血管瘤外科治疗方法对疗效的影响。方法 回顾性总结2013年5月至2017年10月在北京协和医院神经外科行手术治疗的14例颞叶海绵状血管瘤的癫痫患者的临床资料和随访结果。使用国际抗癫痫联盟2001年提出的等级分类方法对患者癫痫控制情况进行评估。结果 无死亡病例。全部患者无远期神经功能障碍。最后一次随访结果显示13例(92.8%)患者近1年无癫痫发作。结论 继发于海绵状血管瘤的颞叶癫痫患者,通过综合评估病史、术前磁共振影像学、术中电生理监测,合理确定手术切除范围,手术治疗可获得良好的治疗效果。

关键词: 癫痫, 颞叶, 海绵状血管瘤, 手术, 预后

Abstract: Objective To investigate the surgical treatment principles of temporal lobe epilepsy caused by cavernous malformation and the surgical resection extent of the cavernous malformation. Methods The clinical data and follow-up results of 14 patients presented with temporal lobe epilepsy due to cavernous malformation admitted to the Department of Neurosurgery of Peking Union Medical College Hospital from May 2013 to Oct 2017 were retrospectively analyzed. The outcome of epilepsy control was assessed by the classification method proposed by International League Against Epilepsy in 2001. Results There were no deaths. No long-term neurological dysfunction was found in all patients. The last follow-up showed that 13 patients (92.8%) had no seizures throughout the year. Conclusion The patients with temporal lobe epilepsy due to cavernous malformation may receive maximized seizure control from surgical treatment, performed after the comprehensive evaluation of the patient's history, preoperative magnetic imaging and electrophysiological monitoring during the operation.

Key words: Epilepsy, Cavernous malformation, Temporal lobe, Surgery, Prognosis

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