基础医学与临床 ›› 2015, Vol. 35 ›› Issue (1): 104-107.
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高丕尧1,高枫2,甘嘉亮1
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摘要: Annexin A5(膜联蛋白A5)是Ca2+依赖的磷脂结合蛋白家族的一名成员,它存在于组织细胞中,因为其具有的独特结构而参加多种细胞内、外的抗凝、促凋亡等重要功能。并且Annexin A5与系统性红斑狼疮、肿瘤等多种疾病的发病机制有着一定关联性。
关键词: Annexin a5, 疾病, 机制
Abstract: Annexin A5 is a member of Ca2+-dependent Phospholipid Binding Proteins Family. It exists in histocytes. And because of its unique structure, Annexin A5 plays an important role in many critical functions such as cell inside/outside anticoagulation and pro-apoptosis. Moreover, Annexin A5 has certain relevance with many diseases such as systemic lupus erythematosus ,tumour and other diseases.
Key words: Annexin a5, Disease, Mechanism
高丕尧 高枫 甘嘉亮. Annexin A5对于部分相关疾病的作用机制研究进展[J]. 基础医学与临床, 2015, 35(1): 104-107.
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