基础医学与临床 ›› 2014, Vol. 34 ›› Issue (8): 1142-1145.

• 短篇综述 • 上一篇    下一篇

雌激素受体GPER与肿瘤

殷立维,闫彦,刘国艺   

  1. 哈尔滨医科大学
  • 收稿日期:2013-11-11 修回日期:2013-12-24 出版日期:2014-08-05 发布日期:2014-07-15
  • 通讯作者: 刘国艺 E-mail:liuguoyi@126.com
  • 基金资助:
    黑龙江省自然科学基金;黑龙江省博士后启动基金

G protein-coupled estrogen receptor and tumor

  • Received:2013-11-11 Revised:2013-12-24 Online:2014-08-05 Published:2014-07-15

摘要: GPER是一种新型的雌激素受体,在人类肿瘤组织和细胞系中广泛表达,并在多种肿瘤细胞,特别是雌激素依赖性肿瘤细胞的增殖、侵袭和转移中扮演重要角色。GPER与肿瘤的相关性研究将为肿瘤的治疗提供新思路。

关键词: GPER, 肿瘤

Abstract: GPER is a novel estrogen receptor, which is widely distributed in human tumor tissues and cell lines. GPER plays an important role in cell proliferation, invasion and migration of a variety of tumors, especially estrogen-dependent tumors. The research on the relationship between GPER and tumor will provide new ideas for tumor therapy.

Key words: GPER, Tumor

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