人造血液的研究进展

doi:10.16352/j.issn.1001-6325.2024.01.0124

基础医学与临床 ›› 2024, Vol. 44 ›› Issue (1): 124-130.doi: 10.16352/j.issn.1001-6325.2024.01.0124

人造血液的研究进展

任烽¹, 金怡杉¹, 陈露¹, 荣龙¹, 余春红^2*

北京航空航天大学 1.生物与医学工程学院;2.医学科学与工程学院,北京 100191

收稿日期:2023-05-19 修回日期:2023-10-30 出版日期:2024-01-05 发布日期:2023-12-25
通讯作者: ^*:chunhongyu@buaa.edu.cn
基金资助:
顺义区“北京市科技成果转化统筹协调与服务平台”建设专项新型人造血(氧载体)的开发(KZ31089801)

Research progress of artificial blood

REN Feng¹, JIN Yishan¹, CHEN Lu¹, RONG Long¹, YU Chunhong^2*

1. School of Biological Science and Medical Engineering;2. School of Medical Science and Engineering, Beihang University, Beijing 100191, China

Received:2023-05-19 Revised:2023-10-30 Online:2024-01-05 Published:2023-12-25
Contact: ^*:chunhongyu@buaa.edu.cn

摘要/Abstract

摘要： 人造血液是一类具有载氧能力、可暂时替代血液部分功能的液体制剂。目前已研制出的人造血液可分为人工合成的血红蛋白、天然血红蛋白制成的人工红细胞、全氟碳化合物和干细胞分化红细胞4大类。本文重点对近年人造血液的国内外研发进展进行总结,并对人造血液在临床上的应用价值、发展趋势及未来研发方向进行初步探讨,以期对该领域的发展提供新思路,推进人造血液产品的临床应用。

关键词: 人造血液, 红细胞, 血红蛋白

Abstract: Artificial blood is a type of liquid preparation with oxygen-loading capacity and can temporarily substitute some function of blood. The developed artificial blood can be divided into four categories: artificial synthetic hemoglobin, artificial red blood cells made from natural hemoglobin, perfluorocarbons, and stem cell-differentiated red blood cells. This review focuses on the domestic and foreign research progress of artificial blood in recent years, and discusses its clinical application value, development trend, and future research, in order to provide new ideas to the development the artificial blood products and promote clinical application.

Key words: artificial blood, erythrocyte, hemoglobin

中图分类号:

R977.8

任烽, 金怡杉, 陈露, 荣龙, 余春红. 人造血液的研究进展[J]. 基础医学与临床, 2024, 44(1): 124-130.

REN Feng, JIN Yishan, CHEN Lu, RONG Long, YU Chunhong. Research progress of artificial blood[J]. Basic & Clinical Medicine, 2024, 44(1): 124-130.

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人造血液的研究进展

Research progress of artificial blood

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