基础医学与临床 ›› 2022, Vol. 42 ›› Issue (8): 1263-1268.doi: 10.16352/j.issn.1001-6325.2022.08.1263

• 临床研究 • 上一篇    下一篇

54例超声心动图引导下先天性心脏病封堵治疗回顾分析

潘广玉, 刘若凡*, 龚达, 刘燊, 佟明汇, 李彬, 许建屏   

  1. 北京大学国际医院 心脏外科, 北京 102206
  • 收稿日期:2021-11-12 修回日期:2022-05-07 出版日期:2022-08-05 发布日期:2022-08-01
  • 通讯作者: *18810488857@126.com
  • 基金资助:
    首都临床诊疗技术研究及示范应用项目(z191100006619005)

Retrospective analysis of occlusion released under guidance of echocardiography in the treatment of 54 patients with congenital heart disease

PAN Guang-yu, LIU Ruo-fan*, GONG Da, LIU Shen, TONG Ming-hui, LI Bin, XU Jian-ping   

  1. Department of Cardiac Surgery,Peking University International Hospital,Beijing 102206, China
  • Received:2021-11-12 Revised:2022-05-07 Online:2022-08-05 Published:2022-08-01
  • Contact: *18810488857@126.com

摘要: 目的 探讨超声引导下房间隔缺损(ASD)和室间隔缺损(VSD)封堵的方法、疗效等临床经验。方法 2010年12月至2019年9月,54例先天性心脏病患者行超声心动图引导下介入封堵手术,其中房间隔缺损30例,室间隔缺损24例。14例ASD采取胸骨右缘第4肋间小切口,经右心房途径封堵;16例ASD通过股静脉穿刺,经血管内途径封堵。24例VSD经剑突下小切口右室前壁途径封堵。结果 经胸封堵24例VSD,均顺利。经胸封堵ASD中,有1例在术后7 h发生封堵器移位,紧急开胸在体外循环直视下取出封堵器,修补ASD。16例经股静脉途径封堵ASD中,手术顺利13例,封堵失败3例,封堵失败后改经胸小切口封堵2例,改体外循环下直视手术1例。46例随访3~103个月,平均(21.3±16.2)个月,未见封堵器移位、脱落、明显残余分流以及其他并发症发生。结论 超声引导下经股静脉途径或经胸小切口房间隔缺损及室间隔缺损封堵安全有效,无射线辐射,操作简单易普及。

关键词: 先天性心脏病, 微创, 封堵术

Abstract: Objective To share our experience of percutaneous or transthoracic closure of atrial septal defect (ASD) and ventricular septal defect (VSD) supported by echocardiography guidance. Methods From December 2010 to September 2019, 54 patients of congenital heart disease (30 cases of isolated atrial septal defect, 24 cases of ventricular septal defect) were treated with surgical operation by occluder under guidance of echocardiography closed without cardiopulmonary bypass. Fourteen cases of ASD were performed device closure through a small right sternal margin thoracotomy incision at the forth intercostal space, 16 cases of ASD underwent percutaneous occlusion surgery, and 24 cases of VSD were closed through small incision under the xiphoid process. Results The operations were successful in the 24 cases of VSD. One of the cases with minimally incision ASD occlusion was displaced 7 hours after operation, the occluder was taken out and ASD was repaired under cardiopulmonary bypass in emergency. There were 13 cases of successful occlusion and 3 cases of failure in percutaneous ASD closure patients. Among three cases, 2 cases underwent ASD closed through transthoracic closure and 1 case underwent open surgery under cardiopulmonary bypass successfully. The 46 cases were followed up for 3-103 months, with an average of (21.3±16.2)months. No occluder displacement, shedding, significant residual shunt were observed. Conclusions Echocardiography-guided percutaneous atrial septal defect and ventricular septal defect is safe and effective without radiation and CPB. Percutaneous closure of atrial septal defect is suitable for children over 3 years. Atrial septal defect and ventricular septal defect occlusion through small thoracic incision is feasible and easy to operate in other healthcare institutions.

Key words: congenital heart disease, minimally invasive surgery, occluder

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