Abstract:

Objective: To report one case of fulminant idiopathic intracranial hypertension (FIIH) associated with intracranial venous sinus stenosis, and explore its clinical characteristics, diagnostic strategies, and the feasibility and efficacy of endovascular treatment. Methods and Results: A 32 - year- old female patient presented with progressive headache and rapid visual deterioration. Imaging findings showed optic nerve sheath dilation, posterior globe flattening, and intracranial venous sinus stenosis. Laboratory tests showed iron deficiency anemia, and lumbar puncture showed markedly elevated cerebrospinal fluid (CSF) pressure (> 330 mm H₂O). The clinical diagnosis was FIIH, right transverse sinus stenosis, and iron deficiency anemia. Emergency venous sinus stenting was performed, resulting in a marked reduction in CSF pressure and significant improvement in visual acuity. Conclusions: There may be a close association between intracranial venous sinus stenosis and FIIH. Early identification and timely intervention are critical for improving prognosis.

Key words: Intracranial hypertension, Cranial sinuses, Constriction, pathologic, Stents, Anemia, iron-deficiency

摘要：

目的: 报道1例颅内静脉窦狭窄并发暴发性特发性颅内压增高患者，探讨暴发性特发性颅内压增高的临床特点、诊断策略及血管内治疗的可行性和有效性。方法与结果: 女性患者，32岁，临床主要表现为进行性头痛及迅速视力下降，影像学检查提示双侧视神经鞘膨胀、双眼球后扁平以及颅内静脉窦狭窄，实验室检查提示缺铁性贫血，腰椎穿刺脑脊液压力显著升高（> 330 mm H₂O）。临床诊断为暴发性特发性颅内压增高、右侧横窦狭窄、缺铁性贫血，紧急行静脉窦支架植入术，术后脑脊液压力下降，视力显著改善。结论: 颅内静脉窦狭窄与暴发性特发性颅内压增高可能存在密切关联，早期识别及干预对改善预后具有重要意义。

关键词: 颅内高压, 颅窦, 缩窄，病理性, 支架, 贫血，缺铁性