Subcortical structures and epilepsy

doi:10.3969/j.issn.1672-6731.2023.03.002

Abstract

Abstract: With the rapid development of neuroelectrophysiology, neuroimaging and other technologies, a large amount of evidence has shown the occurrence and development of epilepsy was closely related to cortico-subcortical neural network. This paper aims to review the relevant studies on the involvement of subcortical structures such as thalamus, hypothalamus, cerebellum, basal ganglia and brainstem in the occurrence and development of epilepsy, as well as some important targets of subcortical nucleus for the treatment of drug-resistant epilepsy (DRE) by neuroregulation, in order to provide help for the exploration of new intervention targets for epilepsy treatment.

Key words: Epilepsy, Cerebral cortex, Nerve net, Electric stimulation therapy, Review

摘要： 随着神经电生理学、神经影像学等技术的快速发展，已有大量证据显示癫痫的发生发展与皮质-皮质下神经网络密切相关。本文拟就丘脑、下丘脑、小脑、基底节、脑干等皮质下结构参与癫痫发生发展的相关研究，以及目前神经调控治疗耐药性癫痫所针对的重要皮质下神经核团靶点进行综述，以为发掘癫痫治疗新靶点提供帮助。

关键词: 癫痫, 大脑皮质, 神经网, 电刺激疗法, 综述

ZHANG Qiong, FENG Li. Subcortical structures and epilepsy[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2023, 23(3): 156-160.

张琼, 冯莉. 大脑皮质下结构与癫痫[J]. 中国现代神经疾病杂志, 2023, 23(3): 156-160.

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URL: https://journal11.magtechjournal.com/cjcnn/EN/10.3969/j.issn.1672-6731.2023.03.002

https://journal11.magtechjournal.com/cjcnn/EN/Y2023/V23/I3/156

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