Significance and progress of the construction of human brain bank for the patients of brain tumors in China

doi:10.3969/j.issn.1672-6731.2022.07.014

Abstract

Abstract: The treatment of brain tumors, especially the malignant brain tumors, has entered in the bottleneck period at present. It is difficult for traditional molecular biology, cell and animal experiments to make a major breakthrough in the treatment of brain tumors, so researchers have turned their attention to the anatomy and pathology of human whole brain tissue. However, the human whole brain tissue which is available for research is extremely deficient. It is of great significance to encourage brain tumors patients to donate organs and establish a standard human brain tissue resource bank of brain tumors (shortened to brain bank) for the research of brain science and providing new treatment ideas for brain tumors, while the construction of brain bank in China started late, with a relatively small scale and relatively slow development. This paper intends to provide guidance for the construction and improvement of brain bank and specific brain tumors related brain bank in China by drawing on the relevant experience of the construction of brain bank in other countries.

Key words: Brain neoplasms, Neuropathology, Autopsy, Human brain bank (not in MeSH), Review

摘要： 脑肿瘤尤其是恶性脑肿瘤的治疗已进入瓶颈期，传统分子生物学、细胞及动物实验在脑肿瘤治疗上再难有重大突破，研究热点重新转向人脑组织解剖学及病理学研究。但可供研究的人脑组织极其缺乏，鼓励脑肿瘤患者进行器官捐献、建立标准的脑肿瘤专病人脑组织资源库（简称脑库）对脑肿瘤治疗、脑科学研究具有重要意义。我国的脑库建设起步较晚，规模较小，发展仍相对缓慢，本文借鉴他国脑库建设经验，为我国脑库及脑肿瘤专病脑库建设及完善提供指导。

关键词: 脑肿瘤, 神经病理学, 尸体解剖, 人脑组织资源库(非MeSH词), 综述

WANG Jun-cheng, ZHAO Yue-yang, MA Dong-ming. Significance and progress of the construction of human brain bank for the patients of brain tumors in China[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2022, 22(7): 635-640.

王军成, 赵岳阳, 马东明. 我国脑肿瘤专病人脑组织资源库建设意义及进展[J]. 中国现代神经疾病杂志, 2022, 22(7): 635-640.

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