Chinese Journal of Contemporary Neurology and Neurosurgery ›› 2020, Vol. 20 ›› Issue (5): 386-391. doi: 10.3969/j.issn.1672-6731.2020.05.004

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Pathophysiological mechanism, clinical classification and treatment strategy of acute progressive large vessel occlusive stroke

DENG Yi-ming, ZHANG Jing-yu, SUN Xuan, SONG Li-gang, LIU Lian, HUO Xiao-chuan, MO Da-peng, MA Ning, GAO Feng, MIAO Zhong-rong   

  1. Department of Interventional Neurology, Beijing Tiantan Hospital, Capital Medical University;China National Clinical Research Center for Neurological Diseases, Beijing 100070, China
  • Received:2020-05-08 Online:2020-05-25 Published:2020-05-19
  • Supported by:

    This study was supported by National Key Research and Development Program of China (No. 2018AAA0102601), Beijing Natural Science Foundation Haidian Original Innovation Jointfund (No. L192010), Beijing Hospitals Authority Youth Programme (No. QML20180506), and Capital Medical University Research Fund (No. PYZ2018080).

急性进展性大血管闭塞性卒中的病理生理学机制、临床分型与治疗策略

邓一鸣, 张净瑜, 孙瑄, 宋立刚, 刘恋, 霍晓川, 莫大鹏, 马宁, 高峰, 缪中荣   

  1. 100070 首都医科大学附属北京天坛医院神经介入中心 国家神经系统疾病临床医学研究中心
  • 通讯作者: 缪中荣,Email:zhongrongm@126.com
  • 基金资助:

    国家重点研发计划项目(项目编号:2018AAA0102601);北京市自然科学基金-海淀原始创新联合基金资助项目(项目编号:L192010);北京市医院管理局青年人才培养"青苗"计划项目(项目编号:QML20180506);首都医科大学科研培育基金资助项目(项目编号:PYZ2018080)

Abstract:

Acute progressive large vessel occlusive stroke (APLVO) is a special kind of acute ischemic stroke with large vessel occlusion (AIS-LVO). Adequate medical history inquiry, detailed imaging analysis and appropriate individualized treatment can lead to better therapeutic effect for APLVO patients. This article reviews the pathophysiological mechanism, clinical features, classification and treatment strategy of APLVO, which different from other causes of ischemic stroke.

Key words: Stroke, Brain ischemia, Arterial occlusive diseases, Review

摘要:

急性进展性大血管闭塞性卒中是特殊类型的急性大血管闭塞性缺血性卒中,通过充分的病史询问、详细的影像学评估和适宜的个体化治疗,可以获得较好预后。本文综述急性进展性大血管闭塞性卒中区别于其他病因缺血性卒中的病理生理学机制、临床特点和分型及治疗策略。

关键词: 卒中, 脑缺血, 动脉闭塞性疾病, 综述