Chinese Journal of Contemporary Neurology and Neurosurgery ›› 2020, Vol. 20 ›› Issue (1): 4-8. doi: 10.3969/j.issn.1672-6731.2020.01.002

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Yesterday, today and tomorrow of autoimmune encephalitis

CHEN Sheng, ZHOU Qin-ming, NI You, LIU Jun   

  1. Department of Neurology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China
  • Received:2020-01-07 Online:2020-01-25 Published:2020-01-21
  • Supported by:

    This study was supported by the National Natural Science Foundation of China (No. 81671241).

自身免疫性脑炎的昨天、今天与明天

陈晟, 周勤明, 倪优, 刘军   

  1. 200025 上海交通大学医学院附属瑞金医院神经科
  • 通讯作者: 刘军,Email:lj11128@rjh.com.cn
  • 基金资助:

    国家自然科学基金资助项目(项目编号:81671241)

Abstract:

Autoimmune encephalitis (AE) is a category of immune-mediated encephalitis, which attracts more and more attention recently. With the development of neuroscience, the antibody spectrum of AE is expanded gradually, and the knowledge of its etiology, pathogenesis and treatment is enriched. Although there are many unknowns, the results of these studies will shed new light to our hope that AE can be successfully treated in the future.

Key words: Encephalitis, Autoimmune diseases, Antoantibodies, Review

摘要:

自身免疫性脑炎是一大类免疫介导的炎症性脑病,近年越来越受到关注。随着神经科学的发展,自身免疫性脑炎抗体谱逐渐扩大,同时不断丰富对其病因、发病机制和治疗的认识。尽管其背后仍存在诸多未知,但相关研究为未来攻克自身免疫性脑炎的难题提供了基础。

关键词: 脑炎, 自身免疫疾病, 自身抗体, 综述