Abstract:

Alzheimer's disease is the most common neurodegenerative disease which gives rise to senile dementia. High morbidity and poor efficacy of Alzheimer's disease have brought about much pressure to the aging society. However, based on early diagnosis, early clinical intervention may slow down the progression of disease and improve its prognosis. In this review, we attempt to introduce the progress of early neuroimaging diagnosis of Alzheimer's disease.

Key words: Alzheimer disease, Cognition disorders, Magnetic resonance imaging, Positron-emission tomography, Review

摘要：

阿尔茨海默病是临床最常见的老年期痴呆类型。在当今老龄化社会中，阿尔茨海默病发病率呈逐年升高之趋势，且治疗效果较差，给社会带来巨大的经济负担。建立在早期诊断基础上的临床干预可以延缓阿尔茨海默病进展，改善患者预后，本文拟对阿尔茨海默病早期诊断的神经影像学进展进行综述。

关键词: 阿尔茨海默病, 认知障碍, 磁共振成像, 正电子发射断层显像术, 综述