Research progress of chronic low-grade inflammation and sleep disorders

doi:10.3969/j.issn.1672-6731.2023.08.004

Abstract

Abstract:

Sleep disorders can lead to persistent immune responses, activate related signal transduction pathways, and keep the body in a low-grade inflammatory state, which is a state of the level of proinflammatory factors is increased but does not cause invasive tissue damage or dysfunction. Long-term persistent chronic low-grade inflammation (CLGI) can promote the occurrence and development of sleep disorders. This article reviews the research progress of CLGI and sleep disorders, and explores new targets for the treatment of sleep disorders.

Key words: Sleep wake disorders, Inflammation, Immune system, Review

摘要：

睡眠障碍可导致持续性免疫反应，激活相关信号转导通路，使机体处于低度炎症状态，是一种促炎因子水平升高但尚未引起浸润组织损伤或功能障碍的状态。长期持续性慢性低度炎症可促进睡眠障碍的发生发展。本文综述慢性低度炎症与睡眠障碍研究进展，为睡眠障碍治疗探寻新的靶点。

关键词: 睡眠觉醒障碍, 炎症, 免疫系统, 综述

Yin LIU, Yong-hong TANG, Jin-xia ZHAI, Yuan QIU. Research progress of chronic low-grade inflammation and sleep disorders[J]. Chinese Journal of Contemporary Neurology and Neurosurgery, 2023, 23(8): 674-677.

刘引, 汤永红, 翟锦霞, 邱媛. 慢性低度炎症与睡眠障碍研究进展[J]. 中国现代神经疾病杂志, 2023, 23(8): 674-677.

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URL: https://journal11.magtechjournal.com/cjcnn/EN/10.3969/j.issn.1672-6731.2023.08.004

https://journal11.magtechjournal.com/cjcnn/EN/Y2023/V23/I8/674

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